Methods for Assessing Expiratory Flow Limitation during Tidal Breathing in COPD Patients
Patients with severe COPD often exhale along the same flow-volume curve during quite breathing as during forced expiratory vital capacity manoeuvre, and this has been taken as indicating expiratory flow limitation at rest (EFLT). Therefore, EFLT, namely, attainment of maximal expiratory flow during...
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| Language: | English |
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Wiley
2012-01-01
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| Series: | Pulmonary Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/234145 |
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| author | Nickolaos G. Koulouris Georgios Kaltsakas Anastasios F. Palamidas Sofia-Antiopi Gennimata |
| author_facet | Nickolaos G. Koulouris Georgios Kaltsakas Anastasios F. Palamidas Sofia-Antiopi Gennimata |
| author_sort | Nickolaos G. Koulouris |
| collection | DOAJ |
| description | Patients with severe COPD often exhale along the same flow-volume curve during quite breathing as during forced expiratory vital capacity manoeuvre, and this has been taken as indicating expiratory flow limitation at rest (EFLT). Therefore, EFLT, namely, attainment of maximal expiratory flow during tidal expiration, occurs when an increase in transpulmonary pressure causes no increase in expiratory flow. EFLT leads to small airway injury and promotes dynamic pulmonary hyperinflation with concurrent dyspnoea and exercise limitation. In fact, EFLT occurs commonly in COPD patients (mainly in GOLD III and IV stage) in whom the latter symptoms are common. The existing up-to-date physiological methods for assessing expiratory flow limitation (EFLT) are reviewed in the present work. Among the currently available techniques, the negative expiratory pressure (NEP) has been validated in a wide variety of settings and disorders. Consequently, it should be regarded as a simple, non invasive, most practical, and accurate new technique. |
| format | Article |
| id | doaj-art-b351d5c7cfeb41f495abe11f2bec070e |
| institution | Kabale University |
| issn | 2090-1836 2090-1844 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pulmonary Medicine |
| spelling | doaj-art-b351d5c7cfeb41f495abe11f2bec070e2025-02-03T05:57:59ZengWileyPulmonary Medicine2090-18362090-18442012-01-01201210.1155/2012/234145234145Methods for Assessing Expiratory Flow Limitation during Tidal Breathing in COPD PatientsNickolaos G. Koulouris0Georgios Kaltsakas1Anastasios F. Palamidas2Sofia-Antiopi Gennimata3Respiratory Function Laboratory, 1st Department of Respiratory Medicine, Medical School, National and Kapodistrian University of Athens and “Sotiria” Chest Disease Hospital, 11527 Athens, GreeceRespiratory Function Laboratory, 1st Department of Respiratory Medicine, Medical School, National and Kapodistrian University of Athens and “Sotiria” Chest Disease Hospital, 11527 Athens, GreeceRespiratory Function Laboratory, 1st Department of Respiratory Medicine, Medical School, National and Kapodistrian University of Athens and “Sotiria” Chest Disease Hospital, 11527 Athens, GreeceRespiratory Function Laboratory, 1st Department of Respiratory Medicine, Medical School, National and Kapodistrian University of Athens and “Sotiria” Chest Disease Hospital, 11527 Athens, GreecePatients with severe COPD often exhale along the same flow-volume curve during quite breathing as during forced expiratory vital capacity manoeuvre, and this has been taken as indicating expiratory flow limitation at rest (EFLT). Therefore, EFLT, namely, attainment of maximal expiratory flow during tidal expiration, occurs when an increase in transpulmonary pressure causes no increase in expiratory flow. EFLT leads to small airway injury and promotes dynamic pulmonary hyperinflation with concurrent dyspnoea and exercise limitation. In fact, EFLT occurs commonly in COPD patients (mainly in GOLD III and IV stage) in whom the latter symptoms are common. The existing up-to-date physiological methods for assessing expiratory flow limitation (EFLT) are reviewed in the present work. Among the currently available techniques, the negative expiratory pressure (NEP) has been validated in a wide variety of settings and disorders. Consequently, it should be regarded as a simple, non invasive, most practical, and accurate new technique.http://dx.doi.org/10.1155/2012/234145 |
| spellingShingle | Nickolaos G. Koulouris Georgios Kaltsakas Anastasios F. Palamidas Sofia-Antiopi Gennimata Methods for Assessing Expiratory Flow Limitation during Tidal Breathing in COPD Patients Pulmonary Medicine |
| title | Methods for Assessing Expiratory Flow Limitation during Tidal Breathing in COPD Patients |
| title_full | Methods for Assessing Expiratory Flow Limitation during Tidal Breathing in COPD Patients |
| title_fullStr | Methods for Assessing Expiratory Flow Limitation during Tidal Breathing in COPD Patients |
| title_full_unstemmed | Methods for Assessing Expiratory Flow Limitation during Tidal Breathing in COPD Patients |
| title_short | Methods for Assessing Expiratory Flow Limitation during Tidal Breathing in COPD Patients |
| title_sort | methods for assessing expiratory flow limitation during tidal breathing in copd patients |
| url | http://dx.doi.org/10.1155/2012/234145 |
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