Critically ill COVID-19 patients with neutralizing autoantibodies against type I interferons have increased risk of herpesvirus disease.
Autoantibodies neutralizing the antiviral action of type I interferons (IFNs) have been associated with predisposition to severe Coronavirus Disease 2019 (COVID-19). Here, we screened for such autoantibodies in 103 critically ill COVID-19 patients in a tertiary intensive care unit (ICU) in Switzerla...
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| Main Authors: | Idoia Busnadiego, Irene A Abela, Pascal M Frey, Daniel A Hofmaenner, Thomas C Scheier, Reto A Schuepbach, Philipp K Buehler, Silvio D Brugger, Benjamin G Hale |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-07-01
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| Series: | PLoS Biology |
| Online Access: | https://doi.org/10.1371/journal.pbio.3001709 |
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