Elevated levels of serum alpha-2-macroglobulin associate with diabetes status and incident CVD in type 1 diabetes

Elevated levels of serum alpha-2-macroglobulin associate with diabetes status and incident CVD in type 1 diabetes

Atherosclerotic CVD is a major cause of death in individuals with type 1 diabetes mellitus (T1DM). However, conventional risk factors do not fully account for the increased risk. This study aimed to investigate whether serum proteins associate with diabetes status and the occurrence of CVD in T1DM....

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Bibliographic Details
Main Authors: Baohai Shao, Janet K. Snell-Bergeon, Ian H. de Boer, W. Sean Davidson, Karin E. Bornfeldt, Jay W. Heinecke
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of Lipid Research
Subjects:
alpha-2-macroglobulin
atherosclerosis
case-cohort design
incident CVD
Cox proportional regression
mass spectrometry
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752500001X
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