A Case of Myomatous Erythrocytosis Syndrome Associated with a Large Uterine Leiomyoma

Several etiologies have been proposed for erythrocytosis associated with uterine leiomyoma. We report a case of erythrocytosis associated with a large uterine leiomyoma, in which specific immunostaining for erythropoietin was positive. A 55-year-old woman, gravida 0, para 0, was referred to our hosp...

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Main Authors: Yosuke Ono, Takao Hidaka, Kaori Fukuta, Keiko Kouchi, Kuniaki Yasoshima, Kiyoshi Takagawa, Takashi Arai
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2014/602139
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author Yosuke Ono
Takao Hidaka
Kaori Fukuta
Keiko Kouchi
Kuniaki Yasoshima
Kiyoshi Takagawa
Takashi Arai
author_facet Yosuke Ono
Takao Hidaka
Kaori Fukuta
Keiko Kouchi
Kuniaki Yasoshima
Kiyoshi Takagawa
Takashi Arai
author_sort Yosuke Ono
collection DOAJ
description Several etiologies have been proposed for erythrocytosis associated with uterine leiomyoma. We report a case of erythrocytosis associated with a large uterine leiomyoma, in which specific immunostaining for erythropoietin was positive. A 55-year-old woman, gravida 0, para 0, was referred to our hospital for treatment for a large uterine myoma and erythrocytosis. She had no vaginal bleeding after she reached menopause at 50 years old. She had severe polycythemia: hemoglobin (Hb), 19.9 g/dL; red blood cell count (RBC), 6.65 × 106/mm3; hematocrit, (Hct) 59.1%. An abdominal simple hysterectomy was performed, and a pathological examination confirmed the diagnosis of leiomyoma of the uterus. In addition, immunostaining demonstrated that the cytoplasm of the leiomyoma cells was strongly positive for erythropoietin. After the operation, the patient’s hemoglobin and hematocrit levels normalized, and we diagnosed her condition as myomatous erythrocytosis syndrome.
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issn 2090-6684
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language English
publishDate 2014-01-01
publisher Wiley
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series Case Reports in Obstetrics and Gynecology
spelling doaj-art-b3265842143f4c018b9843eb3015f6422025-02-03T01:04:58ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922014-01-01201410.1155/2014/602139602139A Case of Myomatous Erythrocytosis Syndrome Associated with a Large Uterine LeiomyomaYosuke Ono0Takao Hidaka1Kaori Fukuta2Keiko Kouchi3Kuniaki Yasoshima4Kiyoshi Takagawa5Takashi Arai6Department of Obstetrics and Gynecology, Kurobe City Hospital, Mikkaichi 1108-1, Kurobe, Toyama, JapanDepartment of Obstetrics and Gynecology, Kurobe City Hospital, Mikkaichi 1108-1, Kurobe, Toyama, JapanDepartment of Obstetrics and Gynecology, Kurobe City Hospital, Mikkaichi 1108-1, Kurobe, Toyama, JapanDepartment of Obstetrics and Gynecology, Kurobe City Hospital, Mikkaichi 1108-1, Kurobe, Toyama, JapanDepartment of Obstetrics and Gynecology, Kurobe City Hospital, Mikkaichi 1108-1, Kurobe, Toyama, JapanDepartment of Pathology, Kurobe City Hospital, Mikkaichi 1108-1, Kurobe, Toyama, JapanDepartment of Obstetrics and Gynecology, Kurobe City Hospital, Mikkaichi 1108-1, Kurobe, Toyama, JapanSeveral etiologies have been proposed for erythrocytosis associated with uterine leiomyoma. We report a case of erythrocytosis associated with a large uterine leiomyoma, in which specific immunostaining for erythropoietin was positive. A 55-year-old woman, gravida 0, para 0, was referred to our hospital for treatment for a large uterine myoma and erythrocytosis. She had no vaginal bleeding after she reached menopause at 50 years old. She had severe polycythemia: hemoglobin (Hb), 19.9 g/dL; red blood cell count (RBC), 6.65 × 106/mm3; hematocrit, (Hct) 59.1%. An abdominal simple hysterectomy was performed, and a pathological examination confirmed the diagnosis of leiomyoma of the uterus. In addition, immunostaining demonstrated that the cytoplasm of the leiomyoma cells was strongly positive for erythropoietin. After the operation, the patient’s hemoglobin and hematocrit levels normalized, and we diagnosed her condition as myomatous erythrocytosis syndrome.http://dx.doi.org/10.1155/2014/602139
spellingShingle Yosuke Ono
Takao Hidaka
Kaori Fukuta
Keiko Kouchi
Kuniaki Yasoshima
Kiyoshi Takagawa
Takashi Arai
A Case of Myomatous Erythrocytosis Syndrome Associated with a Large Uterine Leiomyoma
Case Reports in Obstetrics and Gynecology
title A Case of Myomatous Erythrocytosis Syndrome Associated with a Large Uterine Leiomyoma
title_full A Case of Myomatous Erythrocytosis Syndrome Associated with a Large Uterine Leiomyoma
title_fullStr A Case of Myomatous Erythrocytosis Syndrome Associated with a Large Uterine Leiomyoma
title_full_unstemmed A Case of Myomatous Erythrocytosis Syndrome Associated with a Large Uterine Leiomyoma
title_short A Case of Myomatous Erythrocytosis Syndrome Associated with a Large Uterine Leiomyoma
title_sort case of myomatous erythrocytosis syndrome associated with a large uterine leiomyoma
url http://dx.doi.org/10.1155/2014/602139
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