Attaching artificial Achilles and tibialis cranialis tendons to bone using suture anchors in a rabbit model: assessment of outcomes
Objective The purpose of this study was to investigate the timing and mode of failure of metallic screw-type suture anchors used to attach artificial tendons to bone in an in vivo New Zealand White rabbit model. Study Design Metal suture anchors with braided composite sutures of varying sizes (Unite...
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2025-01-01
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| author | Obinna P. Fidelis Caleb Stubbs Katrina L. Easton Caroline Billings Alisha P. Pedersen David E. Anderson Dustin L. Crouch |
| author_facet | Obinna P. Fidelis Caleb Stubbs Katrina L. Easton Caroline Billings Alisha P. Pedersen David E. Anderson Dustin L. Crouch |
| author_sort | Obinna P. Fidelis |
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| description | Objective The purpose of this study was to investigate the timing and mode of failure of metallic screw-type suture anchors used to attach artificial tendons to bone in an in vivo New Zealand White rabbit model. Study Design Metal suture anchors with braided composite sutures of varying sizes (United States Pharmacopeia (USP) size 1, 2, or 5) were used to secure artificial tendons replacing both the Achilles and tibialis cranialis tendons in 12 female New Zealand White rabbits. Artificial tendons were implanted either at the time of (immediate replacement, n = 8), or four/five weeks after (delayed replacement, n = 4) resection of the biological tendon. Hindlimb radiographs of the rabbits were obtained immediately after surgery and approximately every other week until the study endpoint (16 weeks post-surgery). Results All suture anchors used for the tibialis cranialis artificial tendons remained secure and did not fail during the study. The suture anchor used to attach the Achilles artificial tendon to the calcaneus bone failed in nine of 12 rabbits. In all cases of suture anchor failure, the suture broke away from the knot, while the metallic screw remained securely embedded in the bone. Based on radiographic analysis, the mean estimated failure timepoint was 5.3 ± 2.3 weeks post-surgery, with a range of 2–10 weeks. Statistical analyses (Mann–Whitney U test and Fisher’s exact test) revealed no significant effect of tendon implantation timing or suture size on either the timing or frequency of suture anchor failure. Conclusion For the suture anchors used to attach artificial tendons in this study, suture anchor failure was most likely due to suture wear or cutting against the eyelet of the anchor screw. Future studies are needed to test the effect of suture-eyelet interaction on suture strength under different loading conditions. |
| format | Article |
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| institution | Kabale University |
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| language | English |
| publishDate | 2025-01-01 |
| publisher | PeerJ Inc. |
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| spelling | doaj-art-b3254e71cbc842d48ee710959cca2a7c2025-01-23T15:05:13ZengPeerJ Inc.PeerJ2167-83592025-01-0113e1875610.7717/peerj.18756Attaching artificial Achilles and tibialis cranialis tendons to bone using suture anchors in a rabbit model: assessment of outcomesObinna P. Fidelis0Caleb Stubbs1Katrina L. Easton2Caroline Billings3Alisha P. Pedersen4David E. Anderson5Dustin L. Crouch6College of Engineering, University of Tennessee - Knoxville, TN, United States of AmericaCollege of Engineering, University of Tennessee - Knoxville, TN, United States of AmericaCollege of Engineering, University of Tennessee - Knoxville, TN, United States of AmericaCollege of Veterinary Medicine, University of Tennessee - Knoxville, TN, United States of AmericaCollege of Veterinary Medicine, University of Tennessee - Knoxville, TN, United States of AmericaCollege of Veterinary Medicine, University of Tennessee - Knoxville, TN, United States of AmericaCollege of Engineering, University of Tennessee - Knoxville, TN, United States of AmericaObjective The purpose of this study was to investigate the timing and mode of failure of metallic screw-type suture anchors used to attach artificial tendons to bone in an in vivo New Zealand White rabbit model. Study Design Metal suture anchors with braided composite sutures of varying sizes (United States Pharmacopeia (USP) size 1, 2, or 5) were used to secure artificial tendons replacing both the Achilles and tibialis cranialis tendons in 12 female New Zealand White rabbits. Artificial tendons were implanted either at the time of (immediate replacement, n = 8), or four/five weeks after (delayed replacement, n = 4) resection of the biological tendon. Hindlimb radiographs of the rabbits were obtained immediately after surgery and approximately every other week until the study endpoint (16 weeks post-surgery). Results All suture anchors used for the tibialis cranialis artificial tendons remained secure and did not fail during the study. The suture anchor used to attach the Achilles artificial tendon to the calcaneus bone failed in nine of 12 rabbits. In all cases of suture anchor failure, the suture broke away from the knot, while the metallic screw remained securely embedded in the bone. Based on radiographic analysis, the mean estimated failure timepoint was 5.3 ± 2.3 weeks post-surgery, with a range of 2–10 weeks. Statistical analyses (Mann–Whitney U test and Fisher’s exact test) revealed no significant effect of tendon implantation timing or suture size on either the timing or frequency of suture anchor failure. Conclusion For the suture anchors used to attach artificial tendons in this study, suture anchor failure was most likely due to suture wear or cutting against the eyelet of the anchor screw. Future studies are needed to test the effect of suture-eyelet interaction on suture strength under different loading conditions.https://peerj.com/articles/18756.pdfTendonAnimal modelProsthesisOrthopaedicBiomaterials |
| spellingShingle | Obinna P. Fidelis Caleb Stubbs Katrina L. Easton Caroline Billings Alisha P. Pedersen David E. Anderson Dustin L. Crouch Attaching artificial Achilles and tibialis cranialis tendons to bone using suture anchors in a rabbit model: assessment of outcomes PeerJ Tendon Animal model Prosthesis Orthopaedic Biomaterials |
| title | Attaching artificial Achilles and tibialis cranialis tendons to bone using suture anchors in a rabbit model: assessment of outcomes |
| title_full | Attaching artificial Achilles and tibialis cranialis tendons to bone using suture anchors in a rabbit model: assessment of outcomes |
| title_fullStr | Attaching artificial Achilles and tibialis cranialis tendons to bone using suture anchors in a rabbit model: assessment of outcomes |
| title_full_unstemmed | Attaching artificial Achilles and tibialis cranialis tendons to bone using suture anchors in a rabbit model: assessment of outcomes |
| title_short | Attaching artificial Achilles and tibialis cranialis tendons to bone using suture anchors in a rabbit model: assessment of outcomes |
| title_sort | attaching artificial achilles and tibialis cranialis tendons to bone using suture anchors in a rabbit model assessment of outcomes |
| topic | Tendon Animal model Prosthesis Orthopaedic Biomaterials |
| url | https://peerj.com/articles/18756.pdf |
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