Diagnosis and treatment of depression according to the functional recovery paradigm
Since the appearance of the first antidepressants, ideas about the goals of long-term treatment of depression have changed considerably. The prevailing priority in the 1960s to 1980s of relieving current depressive symptoms and ending the current episode – shifted to achieving remission in the early...
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| Format: | Article |
| Language: | Russian |
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IMA-PRESS LLC
2023-10-01
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| Series: | Неврология, нейропсихиатрия, психосоматика |
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| Online Access: | https://nnp.ima-press.net/nnp/article/view/2108 |
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| _version_ | 1850186600210759680 |
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| author | G. M. Usov |
| author_facet | G. M. Usov |
| author_sort | G. M. Usov |
| collection | DOAJ |
| description | Since the appearance of the first antidepressants, ideas about the goals of long-term treatment of depression have changed considerably. The prevailing priority in the 1960s to 1980s of relieving current depressive symptoms and ending the current episode – shifted to achieving remission in the early 1990s and functional recovery in the mid-2010s. The general recognition of a new approach to the treatment of depression is reflected in the inclusion of functional disorder in the ICD-11 diagnostic criteria for a depressive episode. The paradigm shift in therapy has been driven by advances in the field of psychopharmacology that have led to the development of antidepressants with a fundamentally new mechanism of action that provides a broader therapeutic effect combined with a more favorable tolerability profile. Agomelatine provides a harmonious and complete reduction of depression symptoms, including those resistant to other antidepressants, and a stable clinical and functional remission of high quality, i.e., it allows the achievement of all three therapeutic goals. |
| format | Article |
| id | doaj-art-b307b15ea4ad4d00a37366a917aad3c1 |
| institution | OA Journals |
| issn | 2074-2711 2310-1342 |
| language | Russian |
| publishDate | 2023-10-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Неврология, нейропсихиатрия, психосоматика |
| spelling | doaj-art-b307b15ea4ad4d00a37366a917aad3c12025-08-20T02:16:18ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422023-10-01155798610.14412/2074-2711-2023-5-79-861429Diagnosis and treatment of depression according to the functional recovery paradigmG. M. Usov0Omsk State Medical University, Ministry of Health of the RussiaSince the appearance of the first antidepressants, ideas about the goals of long-term treatment of depression have changed considerably. The prevailing priority in the 1960s to 1980s of relieving current depressive symptoms and ending the current episode – shifted to achieving remission in the early 1990s and functional recovery in the mid-2010s. The general recognition of a new approach to the treatment of depression is reflected in the inclusion of functional disorder in the ICD-11 diagnostic criteria for a depressive episode. The paradigm shift in therapy has been driven by advances in the field of psychopharmacology that have led to the development of antidepressants with a fundamentally new mechanism of action that provides a broader therapeutic effect combined with a more favorable tolerability profile. Agomelatine provides a harmonious and complete reduction of depression symptoms, including those resistant to other antidepressants, and a stable clinical and functional remission of high quality, i.e., it allows the achievement of all three therapeutic goals.https://nnp.ima-press.net/nnp/article/view/2108depressionfunctional recoveryantidepressantsagomelatine |
| spellingShingle | G. M. Usov Diagnosis and treatment of depression according to the functional recovery paradigm Неврология, нейропсихиатрия, психосоматика depression functional recovery antidepressants agomelatine |
| title | Diagnosis and treatment of depression according to the functional recovery paradigm |
| title_full | Diagnosis and treatment of depression according to the functional recovery paradigm |
| title_fullStr | Diagnosis and treatment of depression according to the functional recovery paradigm |
| title_full_unstemmed | Diagnosis and treatment of depression according to the functional recovery paradigm |
| title_short | Diagnosis and treatment of depression according to the functional recovery paradigm |
| title_sort | diagnosis and treatment of depression according to the functional recovery paradigm |
| topic | depression functional recovery antidepressants agomelatine |
| url | https://nnp.ima-press.net/nnp/article/view/2108 |
| work_keys_str_mv | AT gmusov diagnosisandtreatmentofdepressionaccordingtothefunctionalrecoveryparadigm |