Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection
Acute disseminated encephalomyelitis (ADEM) is an inflammatory, demyelinating, and rapidly progressive disorder of the central nervous system. This condition is also known as postinfectious encephalomyelitis, and it is characterized by multifocal lesions in the brain and spinal cord with widespread...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2021/5570566 |
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| author | Ebru Kacmaz Gurkan Bozan Kursat Bora Carman Omer Kilic Mehmet Ozgur Arslanoglu Ugur Toprak Aslı Kavaz Tufan Coskun Yarar Ener Cagri Dinleyici |
| author_facet | Ebru Kacmaz Gurkan Bozan Kursat Bora Carman Omer Kilic Mehmet Ozgur Arslanoglu Ugur Toprak Aslı Kavaz Tufan Coskun Yarar Ener Cagri Dinleyici |
| author_sort | Ebru Kacmaz |
| collection | DOAJ |
| description | Acute disseminated encephalomyelitis (ADEM) is an inflammatory, demyelinating, and rapidly progressive disorder of the central nervous system. This condition is also known as postinfectious encephalomyelitis, and it is characterized by multifocal lesions in the brain and spinal cord with widespread neurological findings. High doses of intravenous (IV) methylprednisolone, intravenous immunoglobulin (IVIG), and plasma exchange (PLEX) treatments comprise the first-line therapy. There are limited pediatric case reports refractory to standard treatment. Here, we present the case of a 17-year-old girl diagnosed with ADEM associated with Salmonella infection, which was treated with rituximab. |
| format | Article |
| id | doaj-art-b2eead33f5e84a21a904bce996ae52f6 |
| institution | Kabale University |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-b2eead33f5e84a21a904bce996ae52f62025-02-03T00:58:59ZengWileyCase Reports in Pediatrics2090-68032090-68112021-01-01202110.1155/2021/55705665570566Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella InfectionEbru Kacmaz0Gurkan Bozan1Kursat Bora Carman2Omer Kilic3Mehmet Ozgur Arslanoglu4Ugur Toprak5Aslı Kavaz Tufan6Coskun Yarar7Ener Cagri Dinleyici8Eskisehir Osmangazi University Faculty of Medicine, Pediatric Intensive Care Unit, Eskisehir, TurkeyEskisehir Osmangazi University Faculty of Medicine, Pediatric Intensive Care Unit, Eskisehir, TurkeyEskisehir Osmangazi University Faculty of Medicine, Department of Pediatric Neurology, Eskisehir, TurkeyEskisehir Osmangazi University Faculty of Medicine, Pediatric Infectious Disease Unit, Eskisehir, TurkeyEskisehir Osmangazi University Faculty of Medicine, Pediatric Intensive Care Unit, Eskisehir, TurkeyEskisehir Osmangazi University Faculty of Medicine, Department of Radiology, Eskisehir, TurkeyEskisehir Osmangazi University Faculty of Medicine, Department of Pediatric Nephrology, Eskisehir, TurkeyEskisehir Osmangazi University Faculty of Medicine, Department of Pediatric Neurology, Eskisehir, TurkeyEskisehir Osmangazi University Faculty of Medicine, Pediatric Intensive Care Unit, Eskisehir, TurkeyAcute disseminated encephalomyelitis (ADEM) is an inflammatory, demyelinating, and rapidly progressive disorder of the central nervous system. This condition is also known as postinfectious encephalomyelitis, and it is characterized by multifocal lesions in the brain and spinal cord with widespread neurological findings. High doses of intravenous (IV) methylprednisolone, intravenous immunoglobulin (IVIG), and plasma exchange (PLEX) treatments comprise the first-line therapy. There are limited pediatric case reports refractory to standard treatment. Here, we present the case of a 17-year-old girl diagnosed with ADEM associated with Salmonella infection, which was treated with rituximab.http://dx.doi.org/10.1155/2021/5570566 |
| spellingShingle | Ebru Kacmaz Gurkan Bozan Kursat Bora Carman Omer Kilic Mehmet Ozgur Arslanoglu Ugur Toprak Aslı Kavaz Tufan Coskun Yarar Ener Cagri Dinleyici Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection Case Reports in Pediatrics |
| title | Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection |
| title_full | Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection |
| title_fullStr | Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection |
| title_full_unstemmed | Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection |
| title_short | Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection |
| title_sort | rituximab treatment in acute disseminated encephalomyelitis associated with salmonella infection |
| url | http://dx.doi.org/10.1155/2021/5570566 |
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