Overexpression of IL-6 and STAT3 may provide new insights into ovine pulmonary adenocarcinoma development

Overexpression of IL-6 and STAT3 may provide new insights into ovine pulmonary adenocarcinoma development

Abstract Background Ovine pulmonary adenocarcinoma (OPA) is caused by Jaagsiekte sheep retrovirus (JSRV) and is considered an important potential animal model for human lung cancer. The precise mechanisms of OPA oncogenesis are still uncertain. The transcription factor signal transducer and activato...

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Main Authors: Corina Toma, Roxana Popa, Lidia Ciobanu, Ioana Baldea, Irina Amorim, Diana Bochynska, Alan Wolfe, Andrada Negoescu, Claudiu Gal, Marian Taulescu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Veterinary Research
Subjects:
Immunohistochemistry
Interleukin-6
Jaagsiekte sheep retrovirus
Oncogenesis
Signal transducer and activator of transcription 3
Western blot
Online Access:https://doi.org/10.1186/s12917-024-04429-6
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https://doi.org/10.1186/s12917-024-04429-6

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