Leptospirosis in Vellore: A Clinical and Serological Study

Leptospirosis is a severe spirochetal zoonosis in the world. It is considered an occupational disease of persons engaged in agriculture, sewage works, forestry, and animal slaughtering. A study was conducted with an objective of assessing the seroprevalence of leptospirosis in and around Vellore dis...

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Main Authors: G. Vimala, A. Mary Josephine Rani, V. Raja Gopal
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:International Journal of Microbiology
Online Access:http://dx.doi.org/10.1155/2014/643940
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author G. Vimala
A. Mary Josephine Rani
V. Raja Gopal
author_facet G. Vimala
A. Mary Josephine Rani
V. Raja Gopal
author_sort G. Vimala
collection DOAJ
description Leptospirosis is a severe spirochetal zoonosis in the world. It is considered an occupational disease of persons engaged in agriculture, sewage works, forestry, and animal slaughtering. A study was conducted with an objective of assessing the seroprevalence of leptospirosis in and around Vellore district, Tamil Nadu. The study was based on the signs and symptoms of the patients reporting fever in Vellore Municipal Clinic (Urban Malarial Scheme). Blood samples were collected from 129 patients. Animal studies were conducted from 24 rodents captured form the market place of the Vellore municipality. In the ZET (Zonal Entomological Team, Vellore) Laboratory the sera were examined by macroscopic slide agglutination test (MSAT). In the MAST, totally 10 positive leptospiral cases from human beings and 10 positive leptospiral cases from rats (Rattus rattus and Rattus norvegicus) were found out. Then both positive cases of leptospiral vials were labeled, sealed, and sent to the Leptospirosis Research Laboratory, Madhavaram, Chennai, for further serovars examination. Among the various serovars identified autumnalis was more prevalent. Our findings showed that the age groups between 15 and 55 years showed more susceptibility. Particularly the adults were more infected. The majority of seropositive individuals in the cases had only subclinical infection. Rodents were abundant and contributed to enzootic and endemic prevalence of leptospirosis.
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spelling doaj-art-b2b534190a8e4d09aaebea8343ec05722025-02-03T05:54:24ZengWileyInternational Journal of Microbiology1687-918X1687-91982014-01-01201410.1155/2014/643940643940Leptospirosis in Vellore: A Clinical and Serological StudyG. Vimala0A. Mary Josephine Rani1V. Raja Gopal2Department of Zoology, Auxilium College, Vellore, Tamil Nadu 632006, IndiaDepartment of Zoology, Auxilium College, Vellore, Tamil Nadu 632006, IndiaZonal Entomological Team, Vellore, Tamil Nadu 632001, IndiaLeptospirosis is a severe spirochetal zoonosis in the world. It is considered an occupational disease of persons engaged in agriculture, sewage works, forestry, and animal slaughtering. A study was conducted with an objective of assessing the seroprevalence of leptospirosis in and around Vellore district, Tamil Nadu. The study was based on the signs and symptoms of the patients reporting fever in Vellore Municipal Clinic (Urban Malarial Scheme). Blood samples were collected from 129 patients. Animal studies were conducted from 24 rodents captured form the market place of the Vellore municipality. In the ZET (Zonal Entomological Team, Vellore) Laboratory the sera were examined by macroscopic slide agglutination test (MSAT). In the MAST, totally 10 positive leptospiral cases from human beings and 10 positive leptospiral cases from rats (Rattus rattus and Rattus norvegicus) were found out. Then both positive cases of leptospiral vials were labeled, sealed, and sent to the Leptospirosis Research Laboratory, Madhavaram, Chennai, for further serovars examination. Among the various serovars identified autumnalis was more prevalent. Our findings showed that the age groups between 15 and 55 years showed more susceptibility. Particularly the adults were more infected. The majority of seropositive individuals in the cases had only subclinical infection. Rodents were abundant and contributed to enzootic and endemic prevalence of leptospirosis.http://dx.doi.org/10.1155/2014/643940
spellingShingle G. Vimala
A. Mary Josephine Rani
V. Raja Gopal
Leptospirosis in Vellore: A Clinical and Serological Study
International Journal of Microbiology
title Leptospirosis in Vellore: A Clinical and Serological Study
title_full Leptospirosis in Vellore: A Clinical and Serological Study
title_fullStr Leptospirosis in Vellore: A Clinical and Serological Study
title_full_unstemmed Leptospirosis in Vellore: A Clinical and Serological Study
title_short Leptospirosis in Vellore: A Clinical and Serological Study
title_sort leptospirosis in vellore a clinical and serological study
url http://dx.doi.org/10.1155/2014/643940
work_keys_str_mv AT gvimala leptospirosisinvelloreaclinicalandserologicalstudy
AT amaryjosephinerani leptospirosisinvelloreaclinicalandserologicalstudy
AT vrajagopal leptospirosisinvelloreaclinicalandserologicalstudy