Characterization of novel phage pK3–24 targeting multidrug-resistant Klebsiella pneumoniae and its therapeutic efficacy in Galleria mellonella larvae

Characterization of novel phage pK3–24 targeting multidrug-resistant Klebsiella pneumoniae and its therapeutic efficacy in Galleria mellonella larvae

Klebsiella pneumoniae is a common, conditionally pathogenic bacterium that often has a multidrug-resistant phenotype, leading to failure of antibiotic therapies. It can therefore induce serious diseases, including community-acquired pneumonia and bloodstream infections. As an emerging alternative to...

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Bibliographic Details
Main Authors: Junxia Feng, Xiaohu Cui, Bing Du, Jinfeng Chen, Guanhua Xue, Lin Gan, Yanling Feng, Zheng Fan, Yuehua Ke, Jinghua Cui, Tongtong Fu, Hanqing Zhao, Chao Yan, Ziying Xu, Yang Yang, Zihui Yu, Lijuan Huang, Shuo Zhao, Ziyan Tian, Zanbo Ding, Yujie Chen, Zhoufei Li, Jing Yuan
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Virus Research
Subjects:
Klebsiella pneumoniae
Phage
Phage therapy
Biofilm
Genomic analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170224001746
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