Host-Parasite Interactions in Individuals with Type 1 and 2 Diabetes Result in Higher Frequency of Ascaris lumbricoides and Giardia lamblia in Type 2 Diabetic Individuals
Host-parasite interactions in diabetic patients might influence diabetes complications and intestinal parasitosis. The aim was to investigate the occurrence of enteroparasites in individuals with diabetes types 1 and 2. A descriptive study was designed to estimate frequencies of parasites and to com...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2018/4238435 |
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| author | Eleuza Rodrigues Machado Núbia Oliveira Matos Sinione Morais Rezende Daniela Carlos Thauana Cristina Silva Leônia Rodrigues Maria Jarlene Rodrigues Almeida Maria Regina Fernandes de Oliveira Maria Imaculada Muniz-Junqueira Rodrigo Gurgel-Gonçalves |
| author_facet | Eleuza Rodrigues Machado Núbia Oliveira Matos Sinione Morais Rezende Daniela Carlos Thauana Cristina Silva Leônia Rodrigues Maria Jarlene Rodrigues Almeida Maria Regina Fernandes de Oliveira Maria Imaculada Muniz-Junqueira Rodrigo Gurgel-Gonçalves |
| author_sort | Eleuza Rodrigues Machado |
| collection | DOAJ |
| description | Host-parasite interactions in diabetic patients might influence diabetes complications and intestinal parasitosis. The aim was to investigate the occurrence of enteroparasites in individuals with diabetes types 1 and 2. A descriptive study was designed to estimate frequencies of parasites and to compare them in individuals with diabetes types 1 and 2 from two Health Centers and one hospital in the Federal District of Brazil. Patients were allocated to the study by convenience. Three fecal samples of 156 diabetic individuals (120 type 1 and 36 type 2) were analyzed using two parasitological methods. Enteroparasites or commensals frequency in diabetics was 64%. Diabetics infected with up to six species of intestinal parasites or commensals were found. Frequencies of Ascaris lumbricoides and Giardia lamblia were higher in individuals with type 2 diabetes. The lower frequency of A. lumbricoides found in type 1 diabetes may be related to a strong Th2 response to parasites. Autoimmune response developed in type 1 diabetic individuals characterized by the production of Th1 cytokines could explain low frequency of G. lamblia. High frequency of parasites found in type 2 diabetes emphasizes the importance of periodic parasitological examinations in these individuals. |
| format | Article |
| id | doaj-art-b25d473bef53455ba102fe47c44a87eb |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-b25d473bef53455ba102fe47c44a87eb2025-02-03T01:03:26ZengWileyJournal of Diabetes Research2314-67452314-67532018-01-01201810.1155/2018/42384354238435Host-Parasite Interactions in Individuals with Type 1 and 2 Diabetes Result in Higher Frequency of Ascaris lumbricoides and Giardia lamblia in Type 2 Diabetic IndividualsEleuza Rodrigues Machado0Núbia Oliveira Matos1Sinione Morais Rezende2Daniela Carlos3Thauana Cristina Silva4Leônia Rodrigues5Maria Jarlene Rodrigues Almeida6Maria Regina Fernandes de Oliveira7Maria Imaculada Muniz-Junqueira8Rodrigo Gurgel-Gonçalves9Curso de Enfermagem, Faculdade Anhanguera de Brasília, Unidade Taguatinga, Universidade Kroton, Taguatinga, DF, BrazilCurso de Enfermagem, Faculdade Anhanguera de Brasília, Unidade Taguatinga, Universidade Kroton, Taguatinga, DF, BrazilCurso de Enfermagem, Faculdade Anhanguera de Brasília, Unidade Taguatinga, Universidade Kroton, Taguatinga, DF, BrazilLaboratório de Imunologia, Departamento de Bioquímica e Imunologia, Faculdade de Medicina, Universidade de São Paulo de Ribeirão Preto, Ribeirão Preto, SP, BrazilCurso de Enfermagem, Faculdade Anhanguera de Brasília, Unidade Taguatinga, Universidade Kroton, Taguatinga, DF, BrazilCurso de Enfermagem, Faculdade Anhanguera de Brasília, Unidade Taguatinga, Universidade Kroton, Taguatinga, DF, BrazilCurso de Enfermagem, Faculdade Anhanguera de Brasília, Unidade Taguatinga, Universidade Kroton, Taguatinga, DF, BrazilNúcleo de Medicina Tropical, Faculdade de Medicina, Universidade de Brasília, Brasilia, DF, BrazilLaboratório de Imunologia Celular, Área de Patologia, Faculdade de Medicina, Universidade de Brasília, Brasilia, DF, BrazilLaboratório de Parasitologia Médica e Biologia de Vetores, Área de Patologia, Faculdade de Medicina, Universidade de Brasília, Asa Norte, 70904-970 Brasilia, DF, BrazilHost-parasite interactions in diabetic patients might influence diabetes complications and intestinal parasitosis. The aim was to investigate the occurrence of enteroparasites in individuals with diabetes types 1 and 2. A descriptive study was designed to estimate frequencies of parasites and to compare them in individuals with diabetes types 1 and 2 from two Health Centers and one hospital in the Federal District of Brazil. Patients were allocated to the study by convenience. Three fecal samples of 156 diabetic individuals (120 type 1 and 36 type 2) were analyzed using two parasitological methods. Enteroparasites or commensals frequency in diabetics was 64%. Diabetics infected with up to six species of intestinal parasites or commensals were found. Frequencies of Ascaris lumbricoides and Giardia lamblia were higher in individuals with type 2 diabetes. The lower frequency of A. lumbricoides found in type 1 diabetes may be related to a strong Th2 response to parasites. Autoimmune response developed in type 1 diabetic individuals characterized by the production of Th1 cytokines could explain low frequency of G. lamblia. High frequency of parasites found in type 2 diabetes emphasizes the importance of periodic parasitological examinations in these individuals.http://dx.doi.org/10.1155/2018/4238435 |
| spellingShingle | Eleuza Rodrigues Machado Núbia Oliveira Matos Sinione Morais Rezende Daniela Carlos Thauana Cristina Silva Leônia Rodrigues Maria Jarlene Rodrigues Almeida Maria Regina Fernandes de Oliveira Maria Imaculada Muniz-Junqueira Rodrigo Gurgel-Gonçalves Host-Parasite Interactions in Individuals with Type 1 and 2 Diabetes Result in Higher Frequency of Ascaris lumbricoides and Giardia lamblia in Type 2 Diabetic Individuals Journal of Diabetes Research |
| title | Host-Parasite Interactions in Individuals with Type 1 and 2 Diabetes Result in Higher Frequency of Ascaris lumbricoides and Giardia lamblia in Type 2 Diabetic Individuals |
| title_full | Host-Parasite Interactions in Individuals with Type 1 and 2 Diabetes Result in Higher Frequency of Ascaris lumbricoides and Giardia lamblia in Type 2 Diabetic Individuals |
| title_fullStr | Host-Parasite Interactions in Individuals with Type 1 and 2 Diabetes Result in Higher Frequency of Ascaris lumbricoides and Giardia lamblia in Type 2 Diabetic Individuals |
| title_full_unstemmed | Host-Parasite Interactions in Individuals with Type 1 and 2 Diabetes Result in Higher Frequency of Ascaris lumbricoides and Giardia lamblia in Type 2 Diabetic Individuals |
| title_short | Host-Parasite Interactions in Individuals with Type 1 and 2 Diabetes Result in Higher Frequency of Ascaris lumbricoides and Giardia lamblia in Type 2 Diabetic Individuals |
| title_sort | host parasite interactions in individuals with type 1 and 2 diabetes result in higher frequency of ascaris lumbricoides and giardia lamblia in type 2 diabetic individuals |
| url | http://dx.doi.org/10.1155/2018/4238435 |
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