Serum Creatinine in Patients with Advanced Liver Disease Is of Limited Value for Identification of Moderate Renal Dysfunction: Are the Equations for Estimating Renal Function Better?
BACKGROUND: The Cockcroft-Gault formula (CGF) is used to estimate the glomerular filtration rate (GFR) based on serum creatinine (Cr) levels, age and sex. A new formula developed by the Modification of Diet in Renal Disease (MDRD) Study Group, based on the patient’s Cr levels, age, sex, race and ser...
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| Format: | Article |
| Language: | English |
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Wiley
2006-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2006/858053 |
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| author | Jillian MacAulay Kara Thompson Bryce A Kiberd David C Barnes Kevork M Peltekian |
| author_facet | Jillian MacAulay Kara Thompson Bryce A Kiberd David C Barnes Kevork M Peltekian |
| author_sort | Jillian MacAulay |
| collection | DOAJ |
| description | BACKGROUND: The Cockcroft-Gault formula (CGF) is used to estimate the glomerular filtration rate (GFR) based on serum creatinine (Cr) levels, age and sex. A new formula developed by the Modification of Diet in Renal Disease (MDRD) Study Group, based on the patient’s Cr levels, age, sex, race and serum urea nitrogen and serum albumin levels, has shown to be more accurate. However, the best formula to identify patients with advanced liver disease (ALD) and moderate renal dysfunction (GFR 60 mL/min/1.73 m2 or less) is not known. The aim of the present study was to compare calculations of GFR, using published formulas (excluding those requiring urine collections) with standard radionuclide measurement of GFR in patients with ALD. |
| format | Article |
| id | doaj-art-b25a077907224cf9898f6ec843c121d3 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2006-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-b25a077907224cf9898f6ec843c121d32025-02-03T01:28:13ZengWileyCanadian Journal of Gastroenterology0835-79002006-01-0120852152610.1155/2006/858053Serum Creatinine in Patients with Advanced Liver Disease Is of Limited Value for Identification of Moderate Renal Dysfunction: Are the Equations for Estimating Renal Function Better?Jillian MacAulay0Kara Thompson1Bryce A Kiberd2David C Barnes3Kevork M Peltekian4Department of Medicine, Division of Gastroenterology (Hepatology Services), Dalhousie University, Halifax, Nova Scotia, CanadaOffice of Medical Outcomes Research and Biostatistics, Dalhousie University, Halifax, Nova Scotia, CanadaDivision of Nephrology, Dalhousie University, Halifax, Nova Scotia, CanadaDepartment of Diagnostic Imaging, Division of Nuclear Medicine, Dalhousie University, Halifax, Nova Scotia, CanadaDepartment of Medicine, Division of Gastroenterology (Hepatology Services), Dalhousie University, Halifax, Nova Scotia, CanadaBACKGROUND: The Cockcroft-Gault formula (CGF) is used to estimate the glomerular filtration rate (GFR) based on serum creatinine (Cr) levels, age and sex. A new formula developed by the Modification of Diet in Renal Disease (MDRD) Study Group, based on the patient’s Cr levels, age, sex, race and serum urea nitrogen and serum albumin levels, has shown to be more accurate. However, the best formula to identify patients with advanced liver disease (ALD) and moderate renal dysfunction (GFR 60 mL/min/1.73 m2 or less) is not known. The aim of the present study was to compare calculations of GFR, using published formulas (excluding those requiring urine collections) with standard radionuclide measurement of GFR in patients with ALD.http://dx.doi.org/10.1155/2006/858053 |
| spellingShingle | Jillian MacAulay Kara Thompson Bryce A Kiberd David C Barnes Kevork M Peltekian Serum Creatinine in Patients with Advanced Liver Disease Is of Limited Value for Identification of Moderate Renal Dysfunction: Are the Equations for Estimating Renal Function Better? Canadian Journal of Gastroenterology |
| title | Serum Creatinine in Patients with Advanced Liver Disease Is of Limited Value for Identification of Moderate Renal Dysfunction: Are the Equations for Estimating Renal Function Better? |
| title_full | Serum Creatinine in Patients with Advanced Liver Disease Is of Limited Value for Identification of Moderate Renal Dysfunction: Are the Equations for Estimating Renal Function Better? |
| title_fullStr | Serum Creatinine in Patients with Advanced Liver Disease Is of Limited Value for Identification of Moderate Renal Dysfunction: Are the Equations for Estimating Renal Function Better? |
| title_full_unstemmed | Serum Creatinine in Patients with Advanced Liver Disease Is of Limited Value for Identification of Moderate Renal Dysfunction: Are the Equations for Estimating Renal Function Better? |
| title_short | Serum Creatinine in Patients with Advanced Liver Disease Is of Limited Value for Identification of Moderate Renal Dysfunction: Are the Equations for Estimating Renal Function Better? |
| title_sort | serum creatinine in patients with advanced liver disease is of limited value for identification of moderate renal dysfunction are the equations for estimating renal function better |
| url | http://dx.doi.org/10.1155/2006/858053 |
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