Time to deterioration of patient-reported outcome endpoints in cancer clinical trials: targeted literature review and best practice recommendations
Abstract Background Time to deterioration (TTD) endpoints are often utilized in the analysis of patient-reported outcome (PRO) data in oncology clinical trials but different endpoint definitions and analysis frameworks exist that can impact result interpretation. This review examined the analysis, r...
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| Main Authors: | Kim Cocks, Bellinda L. King-Kallimanis, Joel Sims, Gill Worthy, Julia Stein, Lara Ayala–Nunes, Monika Achra, Zhanglin Lin Cui, Nalin Payakachat |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2024-12-01
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| Series: | Journal of Patient-Reported Outcomes |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s41687-024-00824-7 |
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