Synthesis, Characterization, and Properties of Sulfonated Chitosan for Protein Adsorption

Chitosan sulfate was prepared and characterized as a new chromatography media for protein separation. The degree of sulfonation of chitosan could be well controlled and impacted under conditions in the synthesis process. The prepared chitosan sulfate shows improved binding capacity with proteins. Su...

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Main Authors: Xiaomin Zhang, Jie Sun
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:International Journal of Polymer Science
Online Access:http://dx.doi.org/10.1155/2020/9876408
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author Xiaomin Zhang
Jie Sun
author_facet Xiaomin Zhang
Jie Sun
author_sort Xiaomin Zhang
collection DOAJ
description Chitosan sulfate was prepared and characterized as a new chromatography media for protein separation. The degree of sulfonation of chitosan could be well controlled and impacted under conditions in the synthesis process. The prepared chitosan sulfate shows improved binding capacity with proteins. Sulfonated chitosan shows improved ion-exchange adsorption properties with proteins, which could have good potential in protein purification.
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institution Kabale University
issn 1687-9422
1687-9430
language English
publishDate 2020-01-01
publisher Wiley
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series International Journal of Polymer Science
spelling doaj-art-b2060c5385d44c59b2fa2c735bedba692025-02-03T01:04:05ZengWileyInternational Journal of Polymer Science1687-94221687-94302020-01-01202010.1155/2020/98764089876408Synthesis, Characterization, and Properties of Sulfonated Chitosan for Protein AdsorptionXiaomin Zhang0Jie Sun1Department of Chemical Engineering, Zhejiang Ocean University, Zhoushan, Zhejiang 316022, ChinaDepartment of Chemical Engineering, Zhejiang Ocean University, Zhoushan, Zhejiang 316022, ChinaChitosan sulfate was prepared and characterized as a new chromatography media for protein separation. The degree of sulfonation of chitosan could be well controlled and impacted under conditions in the synthesis process. The prepared chitosan sulfate shows improved binding capacity with proteins. Sulfonated chitosan shows improved ion-exchange adsorption properties with proteins, which could have good potential in protein purification.http://dx.doi.org/10.1155/2020/9876408
spellingShingle Xiaomin Zhang
Jie Sun
Synthesis, Characterization, and Properties of Sulfonated Chitosan for Protein Adsorption
International Journal of Polymer Science
title Synthesis, Characterization, and Properties of Sulfonated Chitosan for Protein Adsorption
title_full Synthesis, Characterization, and Properties of Sulfonated Chitosan for Protein Adsorption
title_fullStr Synthesis, Characterization, and Properties of Sulfonated Chitosan for Protein Adsorption
title_full_unstemmed Synthesis, Characterization, and Properties of Sulfonated Chitosan for Protein Adsorption
title_short Synthesis, Characterization, and Properties of Sulfonated Chitosan for Protein Adsorption
title_sort synthesis characterization and properties of sulfonated chitosan for protein adsorption
url http://dx.doi.org/10.1155/2020/9876408
work_keys_str_mv AT xiaominzhang synthesischaracterizationandpropertiesofsulfonatedchitosanforproteinadsorption
AT jiesun synthesischaracterizationandpropertiesofsulfonatedchitosanforproteinadsorption