ICU environment as a reservoir of KPC-ST307-Klebsiella pneumoniae high-risk clone resistant to ceftazidime-avibactam

ICU environment as a reservoir of KPC-ST307-Klebsiella pneumoniae high-risk clone resistant to ceftazidime-avibactam

Abstract We characterized all ceftazidime-avibactam-resistant KPC-producing K. pneumoniae (KPC-Kp) isolates recovered from both patients and environmental samples at the ICU of our hospital in 2020, during the COVID-19 pandemic initiation. Antimicrobial susceptibility testing (Sensititre-EUMDROXF; d...

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Bibliographic Details
Main Authors: Marta Hernández-García, Marta Nieto-Torres, Natalia Guerra-Pinto, Juan Antonio Castillo-Polo, Javier Saez de la Fuente, Malkoa Michelena, Manuel Ponce-Alonso, Cruz Soriano-Cuesta, Cristina Díaz-Agero, Rafael Cantón, Teresa M. Coque, Patricia Ruiz-Garbajosa
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
CAZ/AVI-resistance
KPC variants
ST307 K. pneumoniae
Environmental reservoirs
ICU
COVID-19 pandemic
Online Access:https://doi.org/10.1038/s41598-025-14987-w
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