Nanocarriers boost non-systemic fluazinam transportation in plants and microbial community enrichment in soil
Abstract Utilizing nanotechnology for pesticide delivery can enhance their uptake and distribution in plants, thereby boosting pesticide efficiency. Fluazinam, a highly effective broad-spectrum fungicide with unique mode of action, is hindered by its poor systemic conductivity, limiting its field co...
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BMC
2025-01-01
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| Series: | Journal of Nanobiotechnology |
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| Online Access: | https://doi.org/10.1186/s12951-025-03118-2 |
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| author | Wenhui Xiao Jiang Du Yuxin Zheng Shanshan Chen Zhanyun Liu Fengping Chen Feng Liu Beixing Li Xili Liu Can Zhang |
| author_facet | Wenhui Xiao Jiang Du Yuxin Zheng Shanshan Chen Zhanyun Liu Fengping Chen Feng Liu Beixing Li Xili Liu Can Zhang |
| author_sort | Wenhui Xiao |
| collection | DOAJ |
| description | Abstract Utilizing nanotechnology for pesticide delivery can enhance their uptake and distribution in plants, thereby boosting pesticide efficiency. Fluazinam, a highly effective broad-spectrum fungicide with unique mode of action, is hindered by its poor systemic conductivity, limiting its field control efficacy. In this study, fluazinam-loaded nanocapsules were developed, which exhibited significantly higher inhibitory activity against various Phytophthora species compared to the commercial suspension concentrate. Notably, the nanocapsules demonstrated pronounced effects on reducing ATP content in Phytophthora capsici and effectively controlled pepper blight and cucumber downy mildew. Tracking the distribution of fluorescein isothiocyanate (FITC) fluorescein-labeled fluazinam nanocapsules revealed their presence in roots seven days after treatment. High-performance liquid chromatography (HPLC) analysis confirmed the easy absorption and transport of fluazinam nanocapsules by pepper plants. Moreover, treatment with fluazinam nanocapsules significantly increased the expression of two exocytosis genes, FACP and RABF2a, in pepper tissues. Lastly, fluazinam nanocapsules were found to enhance the relative abundance of beneficial bacteria in the soil microbial community. This study presents a promising approach to enhance the upward transport capability of non-systemic pesticides, offering novel insights into their application and improved efficacy. |
| format | Article |
| id | doaj-art-b1e9293484104e7c80262b8107129de8 |
| institution | Kabale University |
| issn | 1477-3155 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Nanobiotechnology |
| spelling | doaj-art-b1e9293484104e7c80262b8107129de82025-02-02T12:41:17ZengBMCJournal of Nanobiotechnology1477-31552025-01-0123111410.1186/s12951-025-03118-2Nanocarriers boost non-systemic fluazinam transportation in plants and microbial community enrichment in soilWenhui Xiao0Jiang Du1Yuxin Zheng2Shanshan Chen3Zhanyun Liu4Fengping Chen5Feng Liu6Beixing Li7Xili Liu8Can Zhang9Department of Plant Pathology, China Agricultural UniversityShandong Provincial Key Laboratory for Biology of Vegetable Diseases and Insect Pests, College of Plant Protection, Shandong Agricultural UniversityDepartment of Plant Pathology, China Agricultural UniversityDepartment of Plant Pathology, China Agricultural UniversityDepartment of Plant Pathology, China Agricultural UniversityState Key Laboratory of Agricultural and Forestry Biosecurity & Key Lab of Biopesticide and Chemical Biology, Ministry of Education, College of Plant Protection, Fujian Agriculture and Forestry UniversityShandong Provincial Key Laboratory for Biology of Vegetable Diseases and Insect Pests, College of Plant Protection, Shandong Agricultural UniversityShandong Provincial Key Laboratory for Biology of Vegetable Diseases and Insect Pests, College of Plant Protection, Shandong Agricultural UniversityDepartment of Plant Pathology, China Agricultural UniversityDepartment of Plant Pathology, China Agricultural UniversityAbstract Utilizing nanotechnology for pesticide delivery can enhance their uptake and distribution in plants, thereby boosting pesticide efficiency. Fluazinam, a highly effective broad-spectrum fungicide with unique mode of action, is hindered by its poor systemic conductivity, limiting its field control efficacy. In this study, fluazinam-loaded nanocapsules were developed, which exhibited significantly higher inhibitory activity against various Phytophthora species compared to the commercial suspension concentrate. Notably, the nanocapsules demonstrated pronounced effects on reducing ATP content in Phytophthora capsici and effectively controlled pepper blight and cucumber downy mildew. Tracking the distribution of fluorescein isothiocyanate (FITC) fluorescein-labeled fluazinam nanocapsules revealed their presence in roots seven days after treatment. High-performance liquid chromatography (HPLC) analysis confirmed the easy absorption and transport of fluazinam nanocapsules by pepper plants. Moreover, treatment with fluazinam nanocapsules significantly increased the expression of two exocytosis genes, FACP and RABF2a, in pepper tissues. Lastly, fluazinam nanocapsules were found to enhance the relative abundance of beneficial bacteria in the soil microbial community. This study presents a promising approach to enhance the upward transport capability of non-systemic pesticides, offering novel insights into their application and improved efficacy.https://doi.org/10.1186/s12951-025-03118-2NanocapsulesNon-systemic pesticidesSoil applicationUpward conductionMicrobial communities |
| spellingShingle | Wenhui Xiao Jiang Du Yuxin Zheng Shanshan Chen Zhanyun Liu Fengping Chen Feng Liu Beixing Li Xili Liu Can Zhang Nanocarriers boost non-systemic fluazinam transportation in plants and microbial community enrichment in soil Journal of Nanobiotechnology Nanocapsules Non-systemic pesticides Soil application Upward conduction Microbial communities |
| title | Nanocarriers boost non-systemic fluazinam transportation in plants and microbial community enrichment in soil |
| title_full | Nanocarriers boost non-systemic fluazinam transportation in plants and microbial community enrichment in soil |
| title_fullStr | Nanocarriers boost non-systemic fluazinam transportation in plants and microbial community enrichment in soil |
| title_full_unstemmed | Nanocarriers boost non-systemic fluazinam transportation in plants and microbial community enrichment in soil |
| title_short | Nanocarriers boost non-systemic fluazinam transportation in plants and microbial community enrichment in soil |
| title_sort | nanocarriers boost non systemic fluazinam transportation in plants and microbial community enrichment in soil |
| topic | Nanocapsules Non-systemic pesticides Soil application Upward conduction Microbial communities |
| url | https://doi.org/10.1186/s12951-025-03118-2 |
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