Granulomatosis with Polyangiitis Localized in the Greater Omentum
Granulomatosis with polyangiitis (GPA) is known as anti-neutrophil cytoplasmic antibody- (ANCA-) associated small vessel vasculitis and typically manifests as pulmonary-renal syndrome, but the disease is not limited to pulmonary or renal systems. The inflammation can involve whole body organs. In ad...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2018/6145903 |
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| _version_ | 1832559025460346880 |
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| author | Ryuji Komine Takashi Kobayashi Hiro Uehara Keisuke Minamimura Kazuhiko Mori Toru Hirata Atsushi Shimizu Masaya Mori |
| author_facet | Ryuji Komine Takashi Kobayashi Hiro Uehara Keisuke Minamimura Kazuhiko Mori Toru Hirata Atsushi Shimizu Masaya Mori |
| author_sort | Ryuji Komine |
| collection | DOAJ |
| description | Granulomatosis with polyangiitis (GPA) is known as anti-neutrophil cytoplasmic antibody- (ANCA-) associated small vessel vasculitis and typically manifests as pulmonary-renal syndrome, but the disease is not limited to pulmonary or renal systems. The inflammation can involve whole body organs. In addition, the ANCA titer does not always become positive. Here, we describe the case of a 91-year-old man who presented with umbilical pain and fever of unknown origin. Only the increased computed tomography value of the greater omentum suggested intra-abdominal inflammation; however, serological examinations, including the ANCA level, could not reveal the focus or cause of symptoms. Finally, the histopathological examination of specimens surgically excised from the greater omentum demonstrated GPA limited to the greater omentum. This report reminds physicians to consider GPA in the differential diagnosis of acute abdominal pain or fever of unknown origin. |
| format | Article |
| id | doaj-art-b1de5580ebb7423796e62cd3d95dfbf6 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-b1de5580ebb7423796e62cd3d95dfbf62025-02-03T01:31:07ZengWileyCase Reports in Surgery2090-69002090-69192018-01-01201810.1155/2018/61459036145903Granulomatosis with Polyangiitis Localized in the Greater OmentumRyuji Komine0Takashi Kobayashi1Hiro Uehara2Keisuke Minamimura3Kazuhiko Mori4Toru Hirata5Atsushi Shimizu6Masaya Mori7Department of Gastroenterological Surgery, Mitsui Memorial Hospital, Tokyo, JapanDepartment of Gastroenterological Surgery, Mitsui Memorial Hospital, Tokyo, JapanDepartment of Gastroenterological Surgery, Mitsui Memorial Hospital, Tokyo, JapanDepartment of Gastroenterological Surgery, Mitsui Memorial Hospital, Tokyo, JapanDepartment of Gastroenterological Surgery, Mitsui Memorial Hospital, Tokyo, JapanDepartment of Gastroenterological Surgery, Mitsui Memorial Hospital, Tokyo, JapanDepartment of Gastroenterological Surgery, Mitsui Memorial Hospital, Tokyo, JapanDepartment of Pathology, Mitsui Memorial Hospital, Tokyo, JapanGranulomatosis with polyangiitis (GPA) is known as anti-neutrophil cytoplasmic antibody- (ANCA-) associated small vessel vasculitis and typically manifests as pulmonary-renal syndrome, but the disease is not limited to pulmonary or renal systems. The inflammation can involve whole body organs. In addition, the ANCA titer does not always become positive. Here, we describe the case of a 91-year-old man who presented with umbilical pain and fever of unknown origin. Only the increased computed tomography value of the greater omentum suggested intra-abdominal inflammation; however, serological examinations, including the ANCA level, could not reveal the focus or cause of symptoms. Finally, the histopathological examination of specimens surgically excised from the greater omentum demonstrated GPA limited to the greater omentum. This report reminds physicians to consider GPA in the differential diagnosis of acute abdominal pain or fever of unknown origin.http://dx.doi.org/10.1155/2018/6145903 |
| spellingShingle | Ryuji Komine Takashi Kobayashi Hiro Uehara Keisuke Minamimura Kazuhiko Mori Toru Hirata Atsushi Shimizu Masaya Mori Granulomatosis with Polyangiitis Localized in the Greater Omentum Case Reports in Surgery |
| title | Granulomatosis with Polyangiitis Localized in the Greater Omentum |
| title_full | Granulomatosis with Polyangiitis Localized in the Greater Omentum |
| title_fullStr | Granulomatosis with Polyangiitis Localized in the Greater Omentum |
| title_full_unstemmed | Granulomatosis with Polyangiitis Localized in the Greater Omentum |
| title_short | Granulomatosis with Polyangiitis Localized in the Greater Omentum |
| title_sort | granulomatosis with polyangiitis localized in the greater omentum |
| url | http://dx.doi.org/10.1155/2018/6145903 |
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