Evaluation of the diagnostic performance of ultrasound for clavicle fractures in emergency settings: A meta-analysis and systematic review

Objective Ultrasound provides real-time, high-resolution imaging and is increasingly recognized as a valuable diagnostic tool for clavicle fractures. Compared with traditional imaging modalities, ultrasound offers advantages such as point-of-care accessibility, absence of radiation exposure, and rap...

Full description

Saved in:
Bibliographic Details
Main Authors: Bin Lin, Danqin Yuan, Weiting Chen, Ying Liu, Xiaozhen Ji
Format: Article
Language:English
Published: SAGE Publishing 2025-06-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605251351273
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849683194529447936
author Bin Lin
Danqin Yuan
Weiting Chen
Ying Liu
Xiaozhen Ji
author_facet Bin Lin
Danqin Yuan
Weiting Chen
Ying Liu
Xiaozhen Ji
author_sort Bin Lin
collection DOAJ
description Objective Ultrasound provides real-time, high-resolution imaging and is increasingly recognized as a valuable diagnostic tool for clavicle fractures. Compared with traditional imaging modalities, ultrasound offers advantages such as point-of-care accessibility, absence of radiation exposure, and rapid diagnosis capability, making it particularly useful in emergency settings. However, the diagnostic performance of ultrasound across different clinical studies remains inconsistent. Therefore, this study aimed to systematically assess the diagnostic accuracy of ultrasound for clavicle fractures through a meta-analysis of existing studies. Methods A systematic review and meta-analysis was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. A comprehensive search of PubMed, Scopus, Embase, Cochrane Library, and Web of Science was performed until 25 February 2025. Studies reporting the sensitivity, specificity, and overall diagnostic performance of ultrasound for clavicle fractures were included. Data extraction and statistical analysis were performed using Stata version 18.0. Results A meta-analysis of seven eligible studies showed a pooled sensitivity of 92% (95% confidence interval: 87%–95%) and pooled specificity of 95% (95% confidence interval: 91%–98%), indicating relatively high diagnostic accuracy. Sensitivity showed low-to-moderate heterogeneity, whereas specificity demonstrated significant heterogeneity. Fagan plot and likelihood ratio analysis supported the clinical utility of ultrasound for both confirming and excluding clavicle fractures. The likelihood ratio scattergram indicated that ultrasound shows good performance in ruling in clavicle fractures but only moderately good performance in ruling them out. Conclusion Current evidence indicates that ultrasound is a promising, noninvasive diagnostic modality for clavicle fractures, especially in emergency settings. Its diagnostic accuracy, coupled with its safety profile, makes it a potentially valuable tool. Nevertheless, standardization of scanning protocols and further validation in diverse populations are needed. Future studies are warranted to standardize scanning protocols, evaluate operator-dependent factors, and validate findings across broader clinical settings. Trial registration number: PROSPERO CRD: 42025643069.
format Article
id doaj-art-b1de27e45cf14490a94e958cb9d5fabe
institution DOAJ
issn 1473-2300
language English
publishDate 2025-06-01
publisher SAGE Publishing
record_format Article
series Journal of International Medical Research
spelling doaj-art-b1de27e45cf14490a94e958cb9d5fabe2025-08-20T03:23:59ZengSAGE PublishingJournal of International Medical Research1473-23002025-06-015310.1177/03000605251351273Evaluation of the diagnostic performance of ultrasound for clavicle fractures in emergency settings: A meta-analysis and systematic reviewBin LinDanqin YuanWeiting ChenYing LiuXiaozhen JiObjective Ultrasound provides real-time, high-resolution imaging and is increasingly recognized as a valuable diagnostic tool for clavicle fractures. Compared with traditional imaging modalities, ultrasound offers advantages such as point-of-care accessibility, absence of radiation exposure, and rapid diagnosis capability, making it particularly useful in emergency settings. However, the diagnostic performance of ultrasound across different clinical studies remains inconsistent. Therefore, this study aimed to systematically assess the diagnostic accuracy of ultrasound for clavicle fractures through a meta-analysis of existing studies. Methods A systematic review and meta-analysis was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. A comprehensive search of PubMed, Scopus, Embase, Cochrane Library, and Web of Science was performed until 25 February 2025. Studies reporting the sensitivity, specificity, and overall diagnostic performance of ultrasound for clavicle fractures were included. Data extraction and statistical analysis were performed using Stata version 18.0. Results A meta-analysis of seven eligible studies showed a pooled sensitivity of 92% (95% confidence interval: 87%–95%) and pooled specificity of 95% (95% confidence interval: 91%–98%), indicating relatively high diagnostic accuracy. Sensitivity showed low-to-moderate heterogeneity, whereas specificity demonstrated significant heterogeneity. Fagan plot and likelihood ratio analysis supported the clinical utility of ultrasound for both confirming and excluding clavicle fractures. The likelihood ratio scattergram indicated that ultrasound shows good performance in ruling in clavicle fractures but only moderately good performance in ruling them out. Conclusion Current evidence indicates that ultrasound is a promising, noninvasive diagnostic modality for clavicle fractures, especially in emergency settings. Its diagnostic accuracy, coupled with its safety profile, makes it a potentially valuable tool. Nevertheless, standardization of scanning protocols and further validation in diverse populations are needed. Future studies are warranted to standardize scanning protocols, evaluate operator-dependent factors, and validate findings across broader clinical settings. Trial registration number: PROSPERO CRD: 42025643069.https://doi.org/10.1177/03000605251351273
spellingShingle Bin Lin
Danqin Yuan
Weiting Chen
Ying Liu
Xiaozhen Ji
Evaluation of the diagnostic performance of ultrasound for clavicle fractures in emergency settings: A meta-analysis and systematic review
Journal of International Medical Research
title Evaluation of the diagnostic performance of ultrasound for clavicle fractures in emergency settings: A meta-analysis and systematic review
title_full Evaluation of the diagnostic performance of ultrasound for clavicle fractures in emergency settings: A meta-analysis and systematic review
title_fullStr Evaluation of the diagnostic performance of ultrasound for clavicle fractures in emergency settings: A meta-analysis and systematic review
title_full_unstemmed Evaluation of the diagnostic performance of ultrasound for clavicle fractures in emergency settings: A meta-analysis and systematic review
title_short Evaluation of the diagnostic performance of ultrasound for clavicle fractures in emergency settings: A meta-analysis and systematic review
title_sort evaluation of the diagnostic performance of ultrasound for clavicle fractures in emergency settings a meta analysis and systematic review
url https://doi.org/10.1177/03000605251351273
work_keys_str_mv AT binlin evaluationofthediagnosticperformanceofultrasoundforclaviclefracturesinemergencysettingsametaanalysisandsystematicreview
AT danqinyuan evaluationofthediagnosticperformanceofultrasoundforclaviclefracturesinemergencysettingsametaanalysisandsystematicreview
AT weitingchen evaluationofthediagnosticperformanceofultrasoundforclaviclefracturesinemergencysettingsametaanalysisandsystematicreview
AT yingliu evaluationofthediagnosticperformanceofultrasoundforclaviclefracturesinemergencysettingsametaanalysisandsystematicreview
AT xiaozhenji evaluationofthediagnosticperformanceofultrasoundforclaviclefracturesinemergencysettingsametaanalysisandsystematicreview