Henoch-Schönlein Purpura with Adalimumab Therapy for Ulcerative Colitis: A Case Report and Review of the Literature
Tumor necrosis factor-α (TNFα) inhibitor therapy has signified an important milestone in the fight against many rheumatological disorders and inflammatory bowel disease (IBD). Cutaneous adverse events caused by this class of medications are well known but relatively uncommon. Most reactions are mild...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2016/2812980 |
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| author | Joseph J. LaConti Jean A. Donet Jeong Hee Cho-Vega Daniel A. Sussman Dana Ascherman Amar R. Deshpande |
| author_facet | Joseph J. LaConti Jean A. Donet Jeong Hee Cho-Vega Daniel A. Sussman Dana Ascherman Amar R. Deshpande |
| author_sort | Joseph J. LaConti |
| collection | DOAJ |
| description | Tumor necrosis factor-α (TNFα) inhibitor therapy has signified an important milestone in the fight against many rheumatological disorders and inflammatory bowel disease (IBD). Cutaneous adverse events caused by this class of medications are well known but relatively uncommon. Most reactions are mild and rarely warrant treatment withdrawal. Henoch-Schönlein purpura (HSP) is a disease with cutaneous vasculitis, arthritis, and gastrointestinal and renal involvement that is usually seen in children, though the worst complications are typically seen in adults. We present a case of HSP complicating adalimumab treatment in a patient with ulcerative colitis who had achieved endoscopic remission. We review similar cases reported in the literature and discuss the consequences of these autoimmune diseases. |
| format | Article |
| id | doaj-art-b1dda6b2d61d4db789aaf54b2876d76d |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-b1dda6b2d61d4db789aaf54b2876d76d2025-02-03T05:45:38ZengWileyCase Reports in Rheumatology2090-68892090-68972016-01-01201610.1155/2016/28129802812980Henoch-Schönlein Purpura with Adalimumab Therapy for Ulcerative Colitis: A Case Report and Review of the LiteratureJoseph J. LaConti0Jean A. Donet1Jeong Hee Cho-Vega2Daniel A. Sussman3Dana Ascherman4Amar R. Deshpande5Division of Rheumatology, University of Miami Leonard Miller School of Medicine, Miami, FL 33136, USADivision of Gastroenterology, University of Miami Leonard Miller School of Medicine, Miami, FL 33136, USADepartment of Pathology, University of Miami Leonard Miller School of Medicine, Miami, FL 33136, USADivision of Gastroenterology, University of Miami Leonard Miller School of Medicine, Miami, FL 33136, USADivision of Rheumatology, University of Miami Leonard Miller School of Medicine, Miami, FL 33136, USADivision of Gastroenterology, University of Miami Leonard Miller School of Medicine, Miami, FL 33136, USATumor necrosis factor-α (TNFα) inhibitor therapy has signified an important milestone in the fight against many rheumatological disorders and inflammatory bowel disease (IBD). Cutaneous adverse events caused by this class of medications are well known but relatively uncommon. Most reactions are mild and rarely warrant treatment withdrawal. Henoch-Schönlein purpura (HSP) is a disease with cutaneous vasculitis, arthritis, and gastrointestinal and renal involvement that is usually seen in children, though the worst complications are typically seen in adults. We present a case of HSP complicating adalimumab treatment in a patient with ulcerative colitis who had achieved endoscopic remission. We review similar cases reported in the literature and discuss the consequences of these autoimmune diseases.http://dx.doi.org/10.1155/2016/2812980 |
| spellingShingle | Joseph J. LaConti Jean A. Donet Jeong Hee Cho-Vega Daniel A. Sussman Dana Ascherman Amar R. Deshpande Henoch-Schönlein Purpura with Adalimumab Therapy for Ulcerative Colitis: A Case Report and Review of the Literature Case Reports in Rheumatology |
| title | Henoch-Schönlein Purpura with Adalimumab Therapy for Ulcerative Colitis: A Case Report and Review of the Literature |
| title_full | Henoch-Schönlein Purpura with Adalimumab Therapy for Ulcerative Colitis: A Case Report and Review of the Literature |
| title_fullStr | Henoch-Schönlein Purpura with Adalimumab Therapy for Ulcerative Colitis: A Case Report and Review of the Literature |
| title_full_unstemmed | Henoch-Schönlein Purpura with Adalimumab Therapy for Ulcerative Colitis: A Case Report and Review of the Literature |
| title_short | Henoch-Schönlein Purpura with Adalimumab Therapy for Ulcerative Colitis: A Case Report and Review of the Literature |
| title_sort | henoch schonlein purpura with adalimumab therapy for ulcerative colitis a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2016/2812980 |
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