Deep sequencing reveals distinct microRNA-mRNA signatures that differentiate pancreatic neuroendocrine tumor from non-diseased pancreas tissue

Deep sequencing reveals distinct microRNA-mRNA signatures that differentiate pancreatic neuroendocrine tumor from non-diseased pancreas tissue

Abstract Background Only a limited number of biomarkers guide personalized management of pancreatic neuroendocrine tumors (PanNETs). Transcriptome profiling of microRNA (miRs) and mRNA has shown value in segregating PanNETs and identifying patients more likely to respond to treatment. Because miRs a...

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Bibliographic Details
Main Authors: N Matyasovska, N Valkova, M Gala, S Bendikova, A Abdulhamed, V. Palicka, Neil Renwick, Pavol Čekan, Evan Paul
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Cancer
Subjects:
Pancreatic neuroendocrine tumors
MicroRNA
mRNA
Biomarkers
miR-mRNA interaction networks
Online Access:https://doi.org/10.1186/s12885-025-14043-w
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https://doi.org/10.1186/s12885-025-14043-w

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