The Dose-Dependent Effects of Spironolactone on TGF-β1 Expression and the Vulnerability to Atrial Fibrillation in Spontaneously Hypertensive Rats

The Dose-Dependent Effects of Spironolactone on TGF-β1 Expression and the Vulnerability to Atrial Fibrillation in Spontaneously Hypertensive Rats

Objective. This study tends to assess the dose-dependent effects of spironolactone on TGF-β1 expression, atrial fibrosis, and the vulnerability to atrial fibrillation in spontaneously hypertensive rats (SHRs) and tries to clarify the association of atrial fibrosis with the vulnerability to atrial fi...

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Bibliographic Details
Main Authors: Mirong Tang, Yan Chen, Fuqing Sun, Liangliang Yan
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Cardiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2021/9924381
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