Topical Microbicides for the Prevention of Sexually Transmitted Diseases and HIV
The development of novel compounds to reduce the sexual transmission of human immunodeficiency virus (HIV), herpes and other pathogens causing sexually transmitted diseases (STDs) has become a topic of great interest. Condom use is the only readily available measure to reduce successfully the propag...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1999-01-01
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| Series: | Canadian Journal of Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/1999/932936 |
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| Summary: | The development of novel compounds to reduce the sexual
transmission of human immunodeficiency virus (HIV), herpes and
other pathogens causing sexually transmitted diseases (STDs) has
become a topic of great interest. Condom use is the only readily
available measure to reduce successfully the propagation of these
infectious agents. To reduce significantly the probability of
acquiring infection, condoms should be used during all risky
sexual intercourse. More attention is being given to
female-controlled methods for the prevention of HIV infection
because many women are unable to negotiate condom use with their
sexual partners. The development of topical microbicides
constitutes one of the most priori tized research areas in the
field of prevention of STDs/HIV for the World Health Organization,
the National Institutes of Health and the Centers for Disease
Control and Prevention. Because the number of women infected with
HIV, herpes and other pathogens causing STDs is growing
dramatically worldwide, there is an urgent need to develop
innovative preventive measures that can reduce the transmission of
these pathogens with minimal mucosa! irritation, and minimal
effects on the vaginal flora and pH. Some of the existing products
as well as promising new topical microbicicles for the prevention
of sexually transmitted infections are reviewed. |
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| ISSN: | 1180-2332 |