A lectin produced by a Streptomyces species targets mammalian pancreatic acinar cells in mice and humans

A lectin produced by a Streptomyces species targets mammalian pancreatic acinar cells in mice and humans

Abstract Lectins are produced in almost all life forms, can interact with targets (glycans) in a cross-kingdom manner and have served as valuable tools for studying glycobiology. Previously, a bacterial lectin, named Streptomyces hemagglutinin (SHA), was found to agglutinate human type B erythrocyte...

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Bibliographic Details
Main Authors: Janine C. Quijano, Honoka Natsuyama, Alonso Tapia, Karine Bagramyan, Jose A. Ortiz, Jacob Mares, Markus Kalkum, Yoko Fujita-Yamaguchi, Hsun Teresa Ku
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Bacterial lectin
Streptomyces sp. 27S5
Pancreas
Acinar cells
Online Access:https://doi.org/10.1038/s41598-024-80889-y
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