Neoadjuvant Radiation with Concurrent 5-FU Resulting in Complete Pathologic Response in Stage IIIB Squamous Cell Carcinoma of the Urethra
Squamous cell carcinoma (SCC) of the urethra is a rare malignancy, comprising less than 1% of all malignancies. The annual age-adjusted incidence of urethral SCC is 4.3 per million in men and 1.5 per million in women. Due to the rarity of the disease, there are a limited number of prospective random...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2020/7948538 |
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| author | Krishna H. Suthar Meghana Kesireddy Mark Sides Amit Correa Aijan Ukudeyva Rohit Venkatesan |
| author_facet | Krishna H. Suthar Meghana Kesireddy Mark Sides Amit Correa Aijan Ukudeyva Rohit Venkatesan |
| author_sort | Krishna H. Suthar |
| collection | DOAJ |
| description | Squamous cell carcinoma (SCC) of the urethra is a rare malignancy, comprising less than 1% of all malignancies. The annual age-adjusted incidence of urethral SCC is 4.3 per million in men and 1.5 per million in women. Due to the rarity of the disease, there are a limited number of prospective randomized controlled trials to evaluate the optimal management of locally advanced urethral SCC. Here, we present the case of a 47-year-old man with stage IIIB urethral squamous cell cancer that showed complete clinical and pathologic response to neoadjuvant chemoradiation with only 5-flurouracil after incomplete response to traditional chemotherapy with paclitaxel, ifosfamide, and cisplatin (TIP). |
| format | Article |
| id | doaj-art-b1b1910c7d254b5d9ea5571cb6cdbc1b |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-b1b1910c7d254b5d9ea5571cb6cdbc1b2025-02-03T00:59:42ZengWileyCase Reports in Oncological Medicine2090-67062090-67142020-01-01202010.1155/2020/79485387948538Neoadjuvant Radiation with Concurrent 5-FU Resulting in Complete Pathologic Response in Stage IIIB Squamous Cell Carcinoma of the UrethraKrishna H. Suthar0Meghana Kesireddy1Mark Sides2Amit Correa3Aijan Ukudeyva4Rohit Venkatesan5Department of Internal Medicine, University of Texas Medical Branch, USADepartment of Internal Medicine, University of Texas Medical Branch, USADepartment of Internal Medicine, Division of Hematology and Medical Oncology, University of Texas Medical Branch, USADepartment of Internal Medicine, Division of Hematology and Medical Oncology, University of Texas Medical Branch, USADepartment of Pathology, University of Texas Medical Branch, USADivision of Medical Oncology, MD Anderson Cancer Center, USASquamous cell carcinoma (SCC) of the urethra is a rare malignancy, comprising less than 1% of all malignancies. The annual age-adjusted incidence of urethral SCC is 4.3 per million in men and 1.5 per million in women. Due to the rarity of the disease, there are a limited number of prospective randomized controlled trials to evaluate the optimal management of locally advanced urethral SCC. Here, we present the case of a 47-year-old man with stage IIIB urethral squamous cell cancer that showed complete clinical and pathologic response to neoadjuvant chemoradiation with only 5-flurouracil after incomplete response to traditional chemotherapy with paclitaxel, ifosfamide, and cisplatin (TIP).http://dx.doi.org/10.1155/2020/7948538 |
| spellingShingle | Krishna H. Suthar Meghana Kesireddy Mark Sides Amit Correa Aijan Ukudeyva Rohit Venkatesan Neoadjuvant Radiation with Concurrent 5-FU Resulting in Complete Pathologic Response in Stage IIIB Squamous Cell Carcinoma of the Urethra Case Reports in Oncological Medicine |
| title | Neoadjuvant Radiation with Concurrent 5-FU Resulting in Complete Pathologic Response in Stage IIIB Squamous Cell Carcinoma of the Urethra |
| title_full | Neoadjuvant Radiation with Concurrent 5-FU Resulting in Complete Pathologic Response in Stage IIIB Squamous Cell Carcinoma of the Urethra |
| title_fullStr | Neoadjuvant Radiation with Concurrent 5-FU Resulting in Complete Pathologic Response in Stage IIIB Squamous Cell Carcinoma of the Urethra |
| title_full_unstemmed | Neoadjuvant Radiation with Concurrent 5-FU Resulting in Complete Pathologic Response in Stage IIIB Squamous Cell Carcinoma of the Urethra |
| title_short | Neoadjuvant Radiation with Concurrent 5-FU Resulting in Complete Pathologic Response in Stage IIIB Squamous Cell Carcinoma of the Urethra |
| title_sort | neoadjuvant radiation with concurrent 5 fu resulting in complete pathologic response in stage iiib squamous cell carcinoma of the urethra |
| url | http://dx.doi.org/10.1155/2020/7948538 |
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