c-FOS Confers Stem Cell-like Features to Multiple Myeloma Cells in a Bone Marrow Microenvironment

c-FOS Confers Stem Cell-like Features to Multiple Myeloma Cells in a Bone Marrow Microenvironment

Multiple myeloma (MM) is the second most common hematologic malignancy and has a poor prognosis. Although the outcomes of MM have markedly improved with the approval of novel agents, the high incidence of relapse means that MM remains incurable. The bone marrow microenvironment (BMME) contributes to...

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Bibliographic Details
Main Authors: Naoki Osada, Jiro Kikuchi, Sae Matsuoka, Hiroshi Yasui, Sho Ikeda, Naoto Takahashi, Yusuke Furukawa, Hideki Nakasone
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Cells
Subjects:
c-FOS
drug resistance
cancer stem cell
bone marrow microenvironment
multiple myeloma
Online Access:https://www.mdpi.com/2073-4409/14/7/474
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