The Effect of Bilateral, Two-Level Cervical Sympathetic Chain Blocks on Specific Symptom Clusters for Traumatic Brain Injury, Independent of Concomitant PTSD Symptoms
<b>Background/Objectives</b>: The aim of this study was to determine if performing ultrasound-guided, bilateral, two-level cervical sympathetic chain blocks (2LCSBs) (performed on subsequent days) improves symptoms associated with traumatic brain injury (TBI) that do not overlap with pos...
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MDPI AG
2024-11-01
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| author | Sean W. Mulvaney James H. Lynch Sanjay Mahadevan Kyle J. Dineen Kristine L. Rae Olmsted |
| author_facet | Sean W. Mulvaney James H. Lynch Sanjay Mahadevan Kyle J. Dineen Kristine L. Rae Olmsted |
| author_sort | Sean W. Mulvaney |
| collection | DOAJ |
| description | <b>Background/Objectives</b>: The aim of this study was to determine if performing ultrasound-guided, bilateral, two-level cervical sympathetic chain blocks (2LCSBs) (performed on subsequent days) improves symptoms associated with traumatic brain injury (TBI) that do not overlap with posttraumatic stress disorder (PTSD). <b>Methods</b>: A retrospective chart review was conducted between August 2022 and February 2023. We identified twenty patients who received bilateral 2LCSBs for PTSD and anxiety symptoms and who also had a history of TBI. Neurobehavioral Symptom Inventory (NSI) scores were collected at baseline, one week, and one month post treatment in 13 males and 7 females. A sub-analysis of the first ten questions of the NSI, which we identified as not overlapping with PTSD or anxiety symptoms, generated an NSI sub-score. <b>Results</b>: Out of 20 patients, all showed improvement in their NSI scores and NSI sub-scores. The NSI sub-scores had a baseline average of 15.45 (on a 40-point scale); the average score at one week post treatment was 8.30; and that at one month post treatment was 7.80. This represents a 49.51% improvement in TBI symptoms which did not overlap with PTSD or anxiety symptoms between baseline and one month. <b>Conclusions</b>: The use of bilateral 2LCSBs may be helpful in treating patients with TBI, regardless of the presence of comorbid PTSD symptoms. |
| format | Article |
| id | doaj-art-b19cc0c58e7b49e4b0b03adf01c2500d |
| institution | DOAJ |
| issn | 2076-3425 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
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| series | Brain Sciences |
| spelling | doaj-art-b19cc0c58e7b49e4b0b03adf01c2500d2025-08-20T02:53:37ZengMDPI AGBrain Sciences2076-34252024-11-011412119310.3390/brainsci14121193The Effect of Bilateral, Two-Level Cervical Sympathetic Chain Blocks on Specific Symptom Clusters for Traumatic Brain Injury, Independent of Concomitant PTSD SymptomsSean W. Mulvaney0James H. Lynch1Sanjay Mahadevan2Kyle J. Dineen3Kristine L. Rae Olmsted4Department of Military and Emergency Medicine, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD 20814, USADepartment of Military and Emergency Medicine, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD 20814, USAOrthobiologics Research Initiative Inc., 11200 Rockville Pike #230, North Bethesda, MD 20852, USAOrthobiologics Research Initiative Inc., 11200 Rockville Pike #230, North Bethesda, MD 20852, USARTI International, 3040 E Cornwallis Rd., Research Park, NC 27709, USA<b>Background/Objectives</b>: The aim of this study was to determine if performing ultrasound-guided, bilateral, two-level cervical sympathetic chain blocks (2LCSBs) (performed on subsequent days) improves symptoms associated with traumatic brain injury (TBI) that do not overlap with posttraumatic stress disorder (PTSD). <b>Methods</b>: A retrospective chart review was conducted between August 2022 and February 2023. We identified twenty patients who received bilateral 2LCSBs for PTSD and anxiety symptoms and who also had a history of TBI. Neurobehavioral Symptom Inventory (NSI) scores were collected at baseline, one week, and one month post treatment in 13 males and 7 females. A sub-analysis of the first ten questions of the NSI, which we identified as not overlapping with PTSD or anxiety symptoms, generated an NSI sub-score. <b>Results</b>: Out of 20 patients, all showed improvement in their NSI scores and NSI sub-scores. The NSI sub-scores had a baseline average of 15.45 (on a 40-point scale); the average score at one week post treatment was 8.30; and that at one month post treatment was 7.80. This represents a 49.51% improvement in TBI symptoms which did not overlap with PTSD or anxiety symptoms between baseline and one month. <b>Conclusions</b>: The use of bilateral 2LCSBs may be helpful in treating patients with TBI, regardless of the presence of comorbid PTSD symptoms.https://www.mdpi.com/2076-3425/14/12/1193stellate ganglion blocktraumatic brain injuryneurobehavioral symptom inventoryposttraumatic stress disordertwo-level cervical sympathetic chain block |
| spellingShingle | Sean W. Mulvaney James H. Lynch Sanjay Mahadevan Kyle J. Dineen Kristine L. Rae Olmsted The Effect of Bilateral, Two-Level Cervical Sympathetic Chain Blocks on Specific Symptom Clusters for Traumatic Brain Injury, Independent of Concomitant PTSD Symptoms Brain Sciences stellate ganglion block traumatic brain injury neurobehavioral symptom inventory posttraumatic stress disorder two-level cervical sympathetic chain block |
| title | The Effect of Bilateral, Two-Level Cervical Sympathetic Chain Blocks on Specific Symptom Clusters for Traumatic Brain Injury, Independent of Concomitant PTSD Symptoms |
| title_full | The Effect of Bilateral, Two-Level Cervical Sympathetic Chain Blocks on Specific Symptom Clusters for Traumatic Brain Injury, Independent of Concomitant PTSD Symptoms |
| title_fullStr | The Effect of Bilateral, Two-Level Cervical Sympathetic Chain Blocks on Specific Symptom Clusters for Traumatic Brain Injury, Independent of Concomitant PTSD Symptoms |
| title_full_unstemmed | The Effect of Bilateral, Two-Level Cervical Sympathetic Chain Blocks on Specific Symptom Clusters for Traumatic Brain Injury, Independent of Concomitant PTSD Symptoms |
| title_short | The Effect of Bilateral, Two-Level Cervical Sympathetic Chain Blocks on Specific Symptom Clusters for Traumatic Brain Injury, Independent of Concomitant PTSD Symptoms |
| title_sort | effect of bilateral two level cervical sympathetic chain blocks on specific symptom clusters for traumatic brain injury independent of concomitant ptsd symptoms |
| topic | stellate ganglion block traumatic brain injury neurobehavioral symptom inventory posttraumatic stress disorder two-level cervical sympathetic chain block |
| url | https://www.mdpi.com/2076-3425/14/12/1193 |
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