Improving explainability of post-separation suicide attempt prediction models for transitioning service members: insights from the Army Study to Assess Risk and Resilience in Servicemembers — Longitudinal Study

Abstract Risk of U.S. Army soldier suicide-related behaviors increases substantially after separation from service. As universal prevention programs have been unable to resolve this problem, a previously reported machine learning model was developed using pre-separation predictors to target high-ris...

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Main Authors: Emily R. Edwards, Joseph C. Geraci, Sarah M. Gildea, Claire Houtsma, Jacob A. Holdcraft, Chris J. Kennedy, Andrew J. King, Alex Luedtke, Brian P. Marx, James A. Naifeh, Nancy A. Sampson, Murray B. Stein, Robert J. Ursano, Ronald C. Kessler
Format: Article
Language:English
Published: Nature Publishing Group 2025-01-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03248-z
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Summary:Abstract Risk of U.S. Army soldier suicide-related behaviors increases substantially after separation from service. As universal prevention programs have been unable to resolve this problem, a previously reported machine learning model was developed using pre-separation predictors to target high-risk transitioning service members (TSMs) for more intensive interventions. This model is currently being used in a demonstration project. The model is limited, though, in two ways. First, the model was developed and trained in a relatively small cross-validation sample (n = 4044) and would likely be improved if a larger sample was available. Second, the model provides no guidance on subtyping high-risk TSMs. This report presents results of an attempt to refine the model to address these limitations by re-estimating the model in a larger sample (n = 5909) and attempting to develop embedded models for differential risk of post-separation stressful life events (SLEs) known to mediate the association of model predictions with post-separation nonfatal suicide attempts (SAs; n = 4957). Analysis used data from the Army STARRS Longitudinal Surveys. The revised model improved prediction of post-separation SAs in the first year (AUC = 0.85) and second-third years (AUC = 0.77) after separation, but embedded models could not predict post-separation SLEs with enough accuracy to support intervention targeting.
ISSN:2158-3188