Alveolar Ridge Preservation Using Xenogeneic Collagen Matrix and Bone Allograft

Alveolar ridge preservation (ARP) has been shown to prevent postextraction bone loss. The aim of this report is to highlight the clinical, radiographic, and histological outcomes following use of a bilayer xenogeneic collagen matrix (XCM) in combination with freeze-dried bone allograft (FDBA) for AR...

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Main Authors: Andreas O. Parashis, Charalampos J. Kalaitzakis, Dimitris N. Tatakis, Konstantinos Tosios
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:International Journal of Dentistry
Online Access:http://dx.doi.org/10.1155/2014/172854
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author Andreas O. Parashis
Charalampos J. Kalaitzakis
Dimitris N. Tatakis
Konstantinos Tosios
author_facet Andreas O. Parashis
Charalampos J. Kalaitzakis
Dimitris N. Tatakis
Konstantinos Tosios
author_sort Andreas O. Parashis
collection DOAJ
description Alveolar ridge preservation (ARP) has been shown to prevent postextraction bone loss. The aim of this report is to highlight the clinical, radiographic, and histological outcomes following use of a bilayer xenogeneic collagen matrix (XCM) in combination with freeze-dried bone allograft (FDBA) for ARP. Nine patients were treated after extraction of 18 teeth. Following minimal flap elevation and atraumatic extraction, sockets were filled with FDBA. The XCM was adapted to cover the defect and 2-3 mm of adjacent bone and flaps were repositioned. Healing was uneventful in all cases, the XCM remained in place, and any matrix exposure was devoid of further complications. Exposed matrix portions were slowly vascularized and replaced by mature keratinized tissue within 2-3 months. Radiographic and clinical assessment indicated adequate volume of bone for implant placement, with all planned implants placed in acceptable positions. When fixed partial dentures were placed, restorations fulfilled aesthetic demands without requiring further augmentation procedures. Histological and immunohistochemical analysis from 9 sites (4 patients) indicated normal mucosa with complete incorporation of the matrix and absence of inflammatory response. The XCM + FDBA combination resulted in minimal complications and desirable soft and hard tissue therapeutic outcomes, suggesting the feasibility of this approach for ARP.
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spelling doaj-art-b14bf00b69514ff7aa32b6c216737c0f2025-02-03T01:23:18ZengWileyInternational Journal of Dentistry1687-87281687-87362014-01-01201410.1155/2014/172854172854Alveolar Ridge Preservation Using Xenogeneic Collagen Matrix and Bone AllograftAndreas O. Parashis0Charalampos J. Kalaitzakis1Dimitris N. Tatakis2Konstantinos Tosios3Private Practice Limited to Periodontics, 33 Sp. Merkouri Street, 11634 Athens, GreecePrivate Practice Limited to Periodontics, 33 Sp. Merkouri Street, 11634 Athens, GreeceDivision of Periodontology, College of Dentistry, The Ohio State University, Columbus, OH, USADepartment of Oral Pathology and Medicine, University of Athens, Athens, GreeceAlveolar ridge preservation (ARP) has been shown to prevent postextraction bone loss. The aim of this report is to highlight the clinical, radiographic, and histological outcomes following use of a bilayer xenogeneic collagen matrix (XCM) in combination with freeze-dried bone allograft (FDBA) for ARP. Nine patients were treated after extraction of 18 teeth. Following minimal flap elevation and atraumatic extraction, sockets were filled with FDBA. The XCM was adapted to cover the defect and 2-3 mm of adjacent bone and flaps were repositioned. Healing was uneventful in all cases, the XCM remained in place, and any matrix exposure was devoid of further complications. Exposed matrix portions were slowly vascularized and replaced by mature keratinized tissue within 2-3 months. Radiographic and clinical assessment indicated adequate volume of bone for implant placement, with all planned implants placed in acceptable positions. When fixed partial dentures were placed, restorations fulfilled aesthetic demands without requiring further augmentation procedures. Histological and immunohistochemical analysis from 9 sites (4 patients) indicated normal mucosa with complete incorporation of the matrix and absence of inflammatory response. The XCM + FDBA combination resulted in minimal complications and desirable soft and hard tissue therapeutic outcomes, suggesting the feasibility of this approach for ARP.http://dx.doi.org/10.1155/2014/172854
spellingShingle Andreas O. Parashis
Charalampos J. Kalaitzakis
Dimitris N. Tatakis
Konstantinos Tosios
Alveolar Ridge Preservation Using Xenogeneic Collagen Matrix and Bone Allograft
International Journal of Dentistry
title Alveolar Ridge Preservation Using Xenogeneic Collagen Matrix and Bone Allograft
title_full Alveolar Ridge Preservation Using Xenogeneic Collagen Matrix and Bone Allograft
title_fullStr Alveolar Ridge Preservation Using Xenogeneic Collagen Matrix and Bone Allograft
title_full_unstemmed Alveolar Ridge Preservation Using Xenogeneic Collagen Matrix and Bone Allograft
title_short Alveolar Ridge Preservation Using Xenogeneic Collagen Matrix and Bone Allograft
title_sort alveolar ridge preservation using xenogeneic collagen matrix and bone allograft
url http://dx.doi.org/10.1155/2014/172854
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