Advances in Pathogenesis of Sjögren’s Syndrome
Sjögren’s syndrome (SS) is a chronic autoimmune disease of unknown etiology that mainly involves exocrine glands. Patients present with dry mouth and eyes, fever, arthralgia, and other systemic symptoms. In severe cases, the quality of life of patients is affected. At present, there is no cure for S...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2021/5928232 |
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| _version_ | 1832561519131361280 |
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| author | Yao Tian Hongyi Yang Na Liu Yan Li Jie Chen |
| author_facet | Yao Tian Hongyi Yang Na Liu Yan Li Jie Chen |
| author_sort | Yao Tian |
| collection | DOAJ |
| description | Sjögren’s syndrome (SS) is a chronic autoimmune disease of unknown etiology that mainly involves exocrine glands. Patients present with dry mouth and eyes, fever, arthralgia, and other systemic symptoms. In severe cases, the quality of life of patients is affected. At present, there is no cure for SS, and the treatment options are extremely limited. In recent years, studies of patients and animal models have identified abnormalities of immune cell function and cytokines to be involved in SS. A systematic review of the literature may clarify the etiology and pathogenesis of SS, as well as provide a theoretical basis for the development of new drugs for the treatment of SS. |
| format | Article |
| id | doaj-art-b14829ebd5ee440a890c5f75928b6cbf |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-b14829ebd5ee440a890c5f75928b6cbf2025-02-03T01:24:47ZengWileyJournal of Immunology Research2314-88612314-71562021-01-01202110.1155/2021/59282325928232Advances in Pathogenesis of Sjögren’s SyndromeYao Tian0Hongyi Yang1Na Liu2Yan Li3Jie Chen4Department of Rheumatology and Clinical Immunology, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Nanchang, ChinaDepartment of Rheumatology and Clinical Immunology, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Nanchang, ChinaDepartment of Rheumatology and Clinical Immunology, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Nanchang, ChinaDepartment of Rheumatology and Clinical Immunology, The First Affiliated Hospital of Xiamen University, Xiamen, ChinaDepartment of Science and Techonology, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Nanchang, ChinaSjögren’s syndrome (SS) is a chronic autoimmune disease of unknown etiology that mainly involves exocrine glands. Patients present with dry mouth and eyes, fever, arthralgia, and other systemic symptoms. In severe cases, the quality of life of patients is affected. At present, there is no cure for SS, and the treatment options are extremely limited. In recent years, studies of patients and animal models have identified abnormalities of immune cell function and cytokines to be involved in SS. A systematic review of the literature may clarify the etiology and pathogenesis of SS, as well as provide a theoretical basis for the development of new drugs for the treatment of SS.http://dx.doi.org/10.1155/2021/5928232 |
| spellingShingle | Yao Tian Hongyi Yang Na Liu Yan Li Jie Chen Advances in Pathogenesis of Sjögren’s Syndrome Journal of Immunology Research |
| title | Advances in Pathogenesis of Sjögren’s Syndrome |
| title_full | Advances in Pathogenesis of Sjögren’s Syndrome |
| title_fullStr | Advances in Pathogenesis of Sjögren’s Syndrome |
| title_full_unstemmed | Advances in Pathogenesis of Sjögren’s Syndrome |
| title_short | Advances in Pathogenesis of Sjögren’s Syndrome |
| title_sort | advances in pathogenesis of sjogren s syndrome |
| url | http://dx.doi.org/10.1155/2021/5928232 |
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