Investigation of the effects of combination of acetylsalicylic acid and vitamin c on functions of bovine neutrophils in vitro conditions

In this study, the effects of combination of acetylsalicylic acid (ASA) and vitamin C at dilferent doses on functions of bovine neutrophils (polymorphonuclear leucoyte/PMNL), and the effects of dilferent ASA concentrations on accumulation of vitamin C in neutrophils were investigated. Neutrophils we...

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Main Authors: Ahmet Levent Baş, Nuri Başpınar, Muammer Elmas, Seyfullah Haliloğlu, Enver Yazar
Format: Article
Language:English
Published: Selcuk University Press
Series:Eurasian Journal of Veterinary Sciences
Subjects:
Online Access:http://eurasianjvetsci.org/pdf.php3?id=472
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author Ahmet Levent Baş
Nuri Başpınar
Muammer Elmas
Seyfullah Haliloğlu
Enver Yazar
author_facet Ahmet Levent Baş
Nuri Başpınar
Muammer Elmas
Seyfullah Haliloğlu
Enver Yazar
author_sort Ahmet Levent Baş
collection DOAJ
description In this study, the effects of combination of acetylsalicylic acid (ASA) and vitamin C at dilferent doses on functions of bovine neutrophils (polymorphonuclear leucoyte/PMNL), and the effects of dilferent ASA concentrations on accumulation of vitamin C in neutrophils were investigated. Neutrophils were obtained from six healthy Holstein-heifers in University Dairy Herd. Phagocytic and microbicidal activity of PMNL were measured with fluorescent microscopic technique and intracellular vitamin C levels were detenııined by spectrophotometer. Intracellular vitamin C levels were incerased by combination of ASA and vitamin C at different concentrations, bul this increase was not statistically significant. Furthenmore, phagocytic and microbicidal activity of PMNL were not statistically changed by these combinations.
format Article
id doaj-art-b1298a4d5ac145c08b962027c27a5986
institution Kabale University
issn 1309-6958
2146-1953
language English
publisher Selcuk University Press
record_format Article
series Eurasian Journal of Veterinary Sciences
spelling doaj-art-b1298a4d5ac145c08b962027c27a59862025-02-03T11:31:17ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-1953142131138472Investigation of the effects of combination of acetylsalicylic acid and vitamin c on functions of bovine neutrophils in vitro conditionsAhmet Levent Baş0Nuri Başpınar1Muammer Elmas2Seyfullah Haliloğlu3Enver Yazar4S.Ü. Veteriner Fakültesi, Farmakoloji ve Toksikoloji Anabilim Dalı, KONYAS.Ü. Veteriner Fakültesi, Biyokimya Anabilim Dalı, KONYAS.Ü. Veteriner Fakültesi, Farmakoloji ve Toksikoloji Anabilim Dalı, KONYAS.Ü. Veteriner Fakültesi, Biyokimya Anabilim Dalı, KONYAS.Ü. Veteriner Fakültesi, Farmakoloji ve Toksikoloji Anabilim Dalı, KONYAIn this study, the effects of combination of acetylsalicylic acid (ASA) and vitamin C at dilferent doses on functions of bovine neutrophils (polymorphonuclear leucoyte/PMNL), and the effects of dilferent ASA concentrations on accumulation of vitamin C in neutrophils were investigated. Neutrophils were obtained from six healthy Holstein-heifers in University Dairy Herd. Phagocytic and microbicidal activity of PMNL were measured with fluorescent microscopic technique and intracellular vitamin C levels were detenııined by spectrophotometer. Intracellular vitamin C levels were incerased by combination of ASA and vitamin C at different concentrations, bul this increase was not statistically significant. Furthenmore, phagocytic and microbicidal activity of PMNL were not statistically changed by these combinations.http://eurasianjvetsci.org/pdf.php3?id=472acetylsalicylic acidvitamin cneutrophil functionsbovine
spellingShingle Ahmet Levent Baş
Nuri Başpınar
Muammer Elmas
Seyfullah Haliloğlu
Enver Yazar
Investigation of the effects of combination of acetylsalicylic acid and vitamin c on functions of bovine neutrophils in vitro conditions
Eurasian Journal of Veterinary Sciences
acetylsalicylic acid
vitamin c
neutrophil functions
bovine
title Investigation of the effects of combination of acetylsalicylic acid and vitamin c on functions of bovine neutrophils in vitro conditions
title_full Investigation of the effects of combination of acetylsalicylic acid and vitamin c on functions of bovine neutrophils in vitro conditions
title_fullStr Investigation of the effects of combination of acetylsalicylic acid and vitamin c on functions of bovine neutrophils in vitro conditions
title_full_unstemmed Investigation of the effects of combination of acetylsalicylic acid and vitamin c on functions of bovine neutrophils in vitro conditions
title_short Investigation of the effects of combination of acetylsalicylic acid and vitamin c on functions of bovine neutrophils in vitro conditions
title_sort investigation of the effects of combination of acetylsalicylic acid and vitamin c on functions of bovine neutrophils in vitro conditions
topic acetylsalicylic acid
vitamin c
neutrophil functions
bovine
url http://eurasianjvetsci.org/pdf.php3?id=472
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AT muammerelmas investigationoftheeffectsofcombinationofacetylsalicylicacidandvitaminconfunctionsofbovineneutrophilsinvitroconditions
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