Relationship between nerve ultrasonography image and electrophysiology in diabetic polyneuropathy
ABSTRACT Aims/Introduction This study aims to investigate the association between cross‐sectional area (CSA) imaging findings of nerve ultrasound and conventional nerve conduction studies (NCS) for patients with distal symmetric sensorimotor polyneuropathy (DSPN) due to type 2 diabetes mellitus. Mat...
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| Format: | Article |
| Language: | English |
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Wiley
2025-02-01
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| Series: | Journal of Diabetes Investigation |
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| Online Access: | https://doi.org/10.1111/jdi.14353 |
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| author | Pei‐Chen Hsieh Long‐Sun Ro Chun‐Che Chu Ming‐Feng Liao Hong‐Shiu Chang Hung‐Chou Kuo |
| author_facet | Pei‐Chen Hsieh Long‐Sun Ro Chun‐Che Chu Ming‐Feng Liao Hong‐Shiu Chang Hung‐Chou Kuo |
| author_sort | Pei‐Chen Hsieh |
| collection | DOAJ |
| description | ABSTRACT Aims/Introduction This study aims to investigate the association between cross‐sectional area (CSA) imaging findings of nerve ultrasound and conventional nerve conduction studies (NCS) for patients with distal symmetric sensorimotor polyneuropathy (DSPN) due to type 2 diabetes mellitus. Materials and Methods We enrolled 103 patients with type 2 diabetes mellitus and collected their demographic data, modified Michigan Neuropathy Screening Instrument (mMNSI) score, NCS, and ultrasonography images of peripheral nerves. The relationship of ultrasound variables for individual nerves and the ultrasound pattern sum score (UPSS) to conventional NCS findings was investigated. Results A higher grade of DSPN was associated with a notably higher CSA. Multivariate step‐wise regression analysis revealed that the number of abnormal nerves was a positive independent variable for UPSS (β coefficient = 0.4205; P < 0.0001). Of the five nerves studied, abnormalities of the tibial nerve (P ≤ 0.0100) and ulnar nerve (P = 0.052) were the most significant variables. Conclusions The tibial nerve exhibited the most substantial association with elevated UPSS. In addition, a strong correlation was observed between abnormal NCS findings and UPSS in patients with DSPN. |
| format | Article |
| id | doaj-art-b11e86db853e446d9e0b788f2acb7297 |
| institution | Kabale University |
| issn | 2040-1116 2040-1124 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Investigation |
| spelling | doaj-art-b11e86db853e446d9e0b788f2acb72972025-02-01T10:02:01ZengWileyJournal of Diabetes Investigation2040-11162040-11242025-02-0116225726410.1111/jdi.14353Relationship between nerve ultrasonography image and electrophysiology in diabetic polyneuropathyPei‐Chen Hsieh0Long‐Sun Ro1Chun‐Che Chu2Ming‐Feng Liao3Hong‐Shiu Chang4Hung‐Chou Kuo5Department of Neurology Chang Gung Memorial Hospital at Linkou Medical Center and Chang Gung University College of Medicine Taoyuan TaiwanDepartment of Neurology Chang Gung Memorial Hospital at Linkou Medical Center and Chang Gung University College of Medicine Taoyuan TaiwanDepartment of Neurology Chang Gung Memorial Hospital at Linkou Medical Center and Chang Gung University College of Medicine Taoyuan TaiwanDepartment of Neurology Chang Gung Memorial Hospital at Linkou Medical Center and Chang Gung University College of Medicine Taoyuan TaiwanDepartment of Neurology Chang Gung Memorial Hospital at Linkou Medical Center and Chang Gung University College of Medicine Taoyuan TaiwanDepartment of Neurology Chang Gung Memorial Hospital at Linkou Medical Center and Chang Gung University College of Medicine Taoyuan TaiwanABSTRACT Aims/Introduction This study aims to investigate the association between cross‐sectional area (CSA) imaging findings of nerve ultrasound and conventional nerve conduction studies (NCS) for patients with distal symmetric sensorimotor polyneuropathy (DSPN) due to type 2 diabetes mellitus. Materials and Methods We enrolled 103 patients with type 2 diabetes mellitus and collected their demographic data, modified Michigan Neuropathy Screening Instrument (mMNSI) score, NCS, and ultrasonography images of peripheral nerves. The relationship of ultrasound variables for individual nerves and the ultrasound pattern sum score (UPSS) to conventional NCS findings was investigated. Results A higher grade of DSPN was associated with a notably higher CSA. Multivariate step‐wise regression analysis revealed that the number of abnormal nerves was a positive independent variable for UPSS (β coefficient = 0.4205; P < 0.0001). Of the five nerves studied, abnormalities of the tibial nerve (P ≤ 0.0100) and ulnar nerve (P = 0.052) were the most significant variables. Conclusions The tibial nerve exhibited the most substantial association with elevated UPSS. In addition, a strong correlation was observed between abnormal NCS findings and UPSS in patients with DSPN.https://doi.org/10.1111/jdi.14353Diabetic polyneuropathyNerve conduction studiesNerve ultrasound |
| spellingShingle | Pei‐Chen Hsieh Long‐Sun Ro Chun‐Che Chu Ming‐Feng Liao Hong‐Shiu Chang Hung‐Chou Kuo Relationship between nerve ultrasonography image and electrophysiology in diabetic polyneuropathy Journal of Diabetes Investigation Diabetic polyneuropathy Nerve conduction studies Nerve ultrasound |
| title | Relationship between nerve ultrasonography image and electrophysiology in diabetic polyneuropathy |
| title_full | Relationship between nerve ultrasonography image and electrophysiology in diabetic polyneuropathy |
| title_fullStr | Relationship between nerve ultrasonography image and electrophysiology in diabetic polyneuropathy |
| title_full_unstemmed | Relationship between nerve ultrasonography image and electrophysiology in diabetic polyneuropathy |
| title_short | Relationship between nerve ultrasonography image and electrophysiology in diabetic polyneuropathy |
| title_sort | relationship between nerve ultrasonography image and electrophysiology in diabetic polyneuropathy |
| topic | Diabetic polyneuropathy Nerve conduction studies Nerve ultrasound |
| url | https://doi.org/10.1111/jdi.14353 |
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