Resveratrol, a food-derived polyphenol, promotes Melanosomal degradation in skin fibroblasts through coordinated activation of autophagy, lysosomal, and antioxidant pathways

Resveratrol, a food-derived polyphenol, promotes Melanosomal degradation in skin fibroblasts through coordinated activation of autophagy, lysosomal, and antioxidant pathways

Resveratrol, a polyphenol found in grapes and peanuts, is known for diverse biological activities, yet its effects on dermal hyperpigmentation (so-called dark spots) remain unexplored. We investigated resveratrol's ability to enhance melanosomal degradation in human dermal fibroblasts. At conce...

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Bibliographic Details
Main Authors: Saki Okamoto, Saya Kakimaru, Mayuko Koreishi, Mika Sakamoto, Yoshimasa Nakamura, Hideya Ando, Yoshio Tsujino, Ayano Satoh
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of Functional Foods
Subjects:
Antioxidant
Lysosomes
Autophagy
Resveratrol
Skin fibroblasts
Bioactive compounds
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464625000143
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