Anterior mediastinal collision tumor of type AB thymoma and adenocarcinoma: a case report
Collision tumors are defined as the coexistence of two or more histologically distinct tumor types at the same anatomical site. Mediastinal collision tumors constitute an exceptionally rare subtype of these lesions. Clinically and radiologically, the preoperative diagnosis is particularly difficult...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1495627/full |
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| author | Zhongqin Kang Rong Xu Weiya Wang Keyu Yan Yi Liao Lizhi Zhang |
| author_facet | Zhongqin Kang Rong Xu Weiya Wang Keyu Yan Yi Liao Lizhi Zhang |
| author_sort | Zhongqin Kang |
| collection | DOAJ |
| description | Collision tumors are defined as the coexistence of two or more histologically distinct tumor types at the same anatomical site. Mediastinal collision tumors constitute an exceptionally rare subtype of these lesions. Clinically and radiologically, the preoperative diagnosis is particularly difficult due to their complex pathological composition and nonspecific manifestations. Misdiagnoses are common in clinical practice, even with preoperative needle biopsy. Radiologic identification of collision tumors is essential to ensure comprehensive sampling for guiding appropriate treatments. Herein, we report an extremely rare case of mediastinal collision tumor diagnosed by contrast-enhanced chest computed tomography (CT), with pathology confirming type AB thymoma and well-differentiated adenocarcinoma (likely of malignant foregut cyst origin). This case report aims to raise awareness of this rare tumor and to discuss the imaging features based on a systematic review of the literature. |
| format | Article |
| id | doaj-art-b10b8e09bfae421ba4b1ece66aaf25f8 |
| institution | OA Journals |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-b10b8e09bfae421ba4b1ece66aaf25f82025-08-20T02:30:59ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-05-011510.3389/fonc.2025.14956271495627Anterior mediastinal collision tumor of type AB thymoma and adenocarcinoma: a case reportZhongqin Kang0Rong Xu1Weiya Wang2Keyu Yan3Yi Liao4Lizhi Zhang5Departments of Radiology, Luxian People’s Hospital, Luzhou, Sichuan, ChinaDepartments of Radiology, West China Second Hospital of Sichuan University, Chengdu, Sichuan, ChinaDepartments of Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, ChinaDepartments of Pathology, Luxian People’s Hospital, Luzhou, Sichuan, ChinaDepartments of Radiology, West China Second Hospital of Sichuan University, Chengdu, Sichuan, ChinaDepartments of Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan, ChinaCollision tumors are defined as the coexistence of two or more histologically distinct tumor types at the same anatomical site. Mediastinal collision tumors constitute an exceptionally rare subtype of these lesions. Clinically and radiologically, the preoperative diagnosis is particularly difficult due to their complex pathological composition and nonspecific manifestations. Misdiagnoses are common in clinical practice, even with preoperative needle biopsy. Radiologic identification of collision tumors is essential to ensure comprehensive sampling for guiding appropriate treatments. Herein, we report an extremely rare case of mediastinal collision tumor diagnosed by contrast-enhanced chest computed tomography (CT), with pathology confirming type AB thymoma and well-differentiated adenocarcinoma (likely of malignant foregut cyst origin). This case report aims to raise awareness of this rare tumor and to discuss the imaging features based on a systematic review of the literature.https://www.frontiersin.org/articles/10.3389/fonc.2025.1495627/fullcollision tumorforegut cysttype AB thymomaadenocarcinomacomputed tomography |
| spellingShingle | Zhongqin Kang Rong Xu Weiya Wang Keyu Yan Yi Liao Lizhi Zhang Anterior mediastinal collision tumor of type AB thymoma and adenocarcinoma: a case report Frontiers in Oncology collision tumor foregut cyst type AB thymoma adenocarcinoma computed tomography |
| title | Anterior mediastinal collision tumor of type AB thymoma and adenocarcinoma: a case report |
| title_full | Anterior mediastinal collision tumor of type AB thymoma and adenocarcinoma: a case report |
| title_fullStr | Anterior mediastinal collision tumor of type AB thymoma and adenocarcinoma: a case report |
| title_full_unstemmed | Anterior mediastinal collision tumor of type AB thymoma and adenocarcinoma: a case report |
| title_short | Anterior mediastinal collision tumor of type AB thymoma and adenocarcinoma: a case report |
| title_sort | anterior mediastinal collision tumor of type ab thymoma and adenocarcinoma a case report |
| topic | collision tumor foregut cyst type AB thymoma adenocarcinoma computed tomography |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2025.1495627/full |
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