scPDA: denoising protein expression in droplet-based single-cell data
Abstract Droplet-based profiling techniques such as CITE-seq are often contaminated by technical noise. Current computational denoising methods have serious limitations, including a strong reliance on often-unavailable empty droplets or null controls and insufficient efficiency due to ignoring prote...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-025-03686-4 |
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