A Lip Lump: An Unexpected Histological Diagnosis of a Lip Schwannoma
Schwannomas are benign nerve sheath tumours arising from Schwann cells. They comprise 1% of all benign tumours. In the 2016 World Health Organisation Classification of Central Nervous System, they are classified as a tumour of the cranial and paraspinal nerves, Schwannoma 9560/0. A 23-year-old Cauca...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Otolaryngology |
| Online Access: | http://dx.doi.org/10.1155/2017/3107362 |
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| author | Thomas Haigh John Raad Glore David Gouldesbrough Winson Wong |
| author_facet | Thomas Haigh John Raad Glore David Gouldesbrough Winson Wong |
| author_sort | Thomas Haigh |
| collection | DOAJ |
| description | Schwannomas are benign nerve sheath tumours arising from Schwann cells. They comprise 1% of all benign tumours. In the 2016 World Health Organisation Classification of Central Nervous System, they are classified as a tumour of the cranial and paraspinal nerves, Schwannoma 9560/0. A 23-year-old Caucasian lady presented with a seven-month history of a painless right upper lip lump. Examination revealed a small cystic 0.5 cm diameter lesion within the right upper lip. The clinical impression was that of a mucocele. Excision of the lip lesion was performed under local anaesthetic. Histological examination of the excised lesion demonstrated a circumscribed nodule consisting of spindle cells mixed with vascular spaces containing red blood cells and fibrin. Immunohistochemistry for S100 was strongly positive. The findings were consistent with that of a small benign schwannoma. The current consensus is for surgical excision of a conservative nature with no need for margins. If recurrence does occur one needs to consider whether complete enucleation was achieved or whether malignant transformation has occurred. |
| format | Article |
| id | doaj-art-b0c86e2c1a9048969a4d4da77f5937fa |
| institution | Kabale University |
| issn | 2090-6765 2090-6773 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Otolaryngology |
| spelling | doaj-art-b0c86e2c1a9048969a4d4da77f5937fa2025-02-03T06:07:28ZengWileyCase Reports in Otolaryngology2090-67652090-67732017-01-01201710.1155/2017/31073623107362A Lip Lump: An Unexpected Histological Diagnosis of a Lip SchwannomaThomas Haigh0John Raad Glore1David Gouldesbrough2Winson Wong3Bradford Teaching Hospitals NHS Foundation Trust, Bradford BD9 6RJ, UKBradford Teaching Hospitals NHS Foundation Trust, Bradford BD9 6RJ, UKBradford Teaching Hospitals NHS Foundation Trust, Bradford BD9 6RJ, UKBradford Teaching Hospitals NHS Foundation Trust, University of Leeds, UKSchwannomas are benign nerve sheath tumours arising from Schwann cells. They comprise 1% of all benign tumours. In the 2016 World Health Organisation Classification of Central Nervous System, they are classified as a tumour of the cranial and paraspinal nerves, Schwannoma 9560/0. A 23-year-old Caucasian lady presented with a seven-month history of a painless right upper lip lump. Examination revealed a small cystic 0.5 cm diameter lesion within the right upper lip. The clinical impression was that of a mucocele. Excision of the lip lesion was performed under local anaesthetic. Histological examination of the excised lesion demonstrated a circumscribed nodule consisting of spindle cells mixed with vascular spaces containing red blood cells and fibrin. Immunohistochemistry for S100 was strongly positive. The findings were consistent with that of a small benign schwannoma. The current consensus is for surgical excision of a conservative nature with no need for margins. If recurrence does occur one needs to consider whether complete enucleation was achieved or whether malignant transformation has occurred.http://dx.doi.org/10.1155/2017/3107362 |
| spellingShingle | Thomas Haigh John Raad Glore David Gouldesbrough Winson Wong A Lip Lump: An Unexpected Histological Diagnosis of a Lip Schwannoma Case Reports in Otolaryngology |
| title | A Lip Lump: An Unexpected Histological Diagnosis of a Lip Schwannoma |
| title_full | A Lip Lump: An Unexpected Histological Diagnosis of a Lip Schwannoma |
| title_fullStr | A Lip Lump: An Unexpected Histological Diagnosis of a Lip Schwannoma |
| title_full_unstemmed | A Lip Lump: An Unexpected Histological Diagnosis of a Lip Schwannoma |
| title_short | A Lip Lump: An Unexpected Histological Diagnosis of a Lip Schwannoma |
| title_sort | lip lump an unexpected histological diagnosis of a lip schwannoma |
| url | http://dx.doi.org/10.1155/2017/3107362 |
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