Quantification of Upper Limb Motor Recovery and EEG Power Changes after Robot-Assisted Bilateral Arm Training in Chronic Stroke Patients: A Prospective Pilot Study
Background. Bilateral arm training (BAT) has shown promise in expediting progress toward upper limb recovery in chronic stroke patients, but its neural correlates are poorly understood. Objective. To evaluate changes in upper limb function and EEG power after a robot-assisted BAT in chronic stroke p...
Saved in:
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2018/8105480 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832558952080998400 |
|---|---|
| author | Marialuisa Gandolfi Emanuela Formaggio Christian Geroin Silvia Francesca Storti Ilaria Boscolo Galazzo Marta Bortolami Leopold Saltuari Alessandro Picelli Andreas Waldner Paolo Manganotti Nicola Smania |
| author_facet | Marialuisa Gandolfi Emanuela Formaggio Christian Geroin Silvia Francesca Storti Ilaria Boscolo Galazzo Marta Bortolami Leopold Saltuari Alessandro Picelli Andreas Waldner Paolo Manganotti Nicola Smania |
| author_sort | Marialuisa Gandolfi |
| collection | DOAJ |
| description | Background. Bilateral arm training (BAT) has shown promise in expediting progress toward upper limb recovery in chronic stroke patients, but its neural correlates are poorly understood. Objective. To evaluate changes in upper limb function and EEG power after a robot-assisted BAT in chronic stroke patients. Methods. In a within-subject design, seven right-handed chronic stroke patients with upper limb paresis received 21 sessions (3 days/week) of the robot-assisted BAT. The outcomes were changes in score on the upper limb section of the Fugl-Meyer assessment (FM), Motricity Index (MI), and Modified Ashworth Scale (MAS) evaluated at the baseline (T0), posttraining (T1), and 1-month follow-up (T2). Event-related desynchronization/synchronization were calculated in the upper alpha and the beta frequency ranges. Results. Significant improvement in all outcomes was measured over the course of the study. Changes in FM were significant at T2, and in MAS at T1 and T2. After training, desynchronization on the ipsilesional sensorimotor areas increased during passive and active movement, as compared with T0. Conclusions. A repetitive robotic-assisted BAT program may improve upper limb motor function and reduce spasticity in the chronically impaired paretic arm. Effects on spasticity were associated with EEG changes over the ipsilesional sensorimotor network. |
| format | Article |
| id | doaj-art-b0be6ff479da488fae0217823b64f61f |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-b0be6ff479da488fae0217823b64f61f2025-02-03T01:31:14ZengWileyNeural Plasticity2090-59041687-54432018-01-01201810.1155/2018/81054808105480Quantification of Upper Limb Motor Recovery and EEG Power Changes after Robot-Assisted Bilateral Arm Training in Chronic Stroke Patients: A Prospective Pilot StudyMarialuisa Gandolfi0Emanuela Formaggio1Christian Geroin2Silvia Francesca Storti3Ilaria Boscolo Galazzo4Marta Bortolami5Leopold Saltuari6Alessandro Picelli7Andreas Waldner8Paolo Manganotti9Nicola Smania10Neuromotor and Cognitive Rehabilitation Research Centre (CRRNC), Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, ItalySan Camillo Hospital IRCCS, Venice, ItalyNeuromotor and Cognitive Rehabilitation Research Centre (CRRNC), Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, ItalyDepartment of Computer Science, University of Verona, Verona, ItalyDepartment of Computer Science, University of Verona, Verona, ItalyNeuromotor and Cognitive Rehabilitation Research Centre (CRRNC), Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, ItalyDepartment of Neurology, Hochzirl Hospital, 6170 Zirl, AustriaNeuromotor and Cognitive Rehabilitation Research Centre (CRRNC), Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, ItalyResearch Unit for Neurorehabilitation South Tyrol, 39100 Bolzano, ItalyClinical Unit of Neurology, Department of Medical Sciences, University Hospital and Health Services of Trieste, University of Trieste, Trieste, ItalyNeuromotor and Cognitive Rehabilitation Research Centre (CRRNC), Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, ItalyBackground. Bilateral arm training (BAT) has shown promise in expediting progress toward upper limb recovery in chronic stroke patients, but its neural correlates are poorly understood. Objective. To evaluate changes in upper limb function and EEG power after a robot-assisted BAT in chronic stroke patients. Methods. In a within-subject design, seven right-handed chronic stroke patients with upper limb paresis received 21 sessions (3 days/week) of the robot-assisted BAT. The outcomes were changes in score on the upper limb section of the Fugl-Meyer assessment (FM), Motricity Index (MI), and Modified Ashworth Scale (MAS) evaluated at the baseline (T0), posttraining (T1), and 1-month follow-up (T2). Event-related desynchronization/synchronization were calculated in the upper alpha and the beta frequency ranges. Results. Significant improvement in all outcomes was measured over the course of the study. Changes in FM were significant at T2, and in MAS at T1 and T2. After training, desynchronization on the ipsilesional sensorimotor areas increased during passive and active movement, as compared with T0. Conclusions. A repetitive robotic-assisted BAT program may improve upper limb motor function and reduce spasticity in the chronically impaired paretic arm. Effects on spasticity were associated with EEG changes over the ipsilesional sensorimotor network.http://dx.doi.org/10.1155/2018/8105480 |
| spellingShingle | Marialuisa Gandolfi Emanuela Formaggio Christian Geroin Silvia Francesca Storti Ilaria Boscolo Galazzo Marta Bortolami Leopold Saltuari Alessandro Picelli Andreas Waldner Paolo Manganotti Nicola Smania Quantification of Upper Limb Motor Recovery and EEG Power Changes after Robot-Assisted Bilateral Arm Training in Chronic Stroke Patients: A Prospective Pilot Study Neural Plasticity |
| title | Quantification of Upper Limb Motor Recovery and EEG Power Changes after Robot-Assisted Bilateral Arm Training in Chronic Stroke Patients: A Prospective Pilot Study |
| title_full | Quantification of Upper Limb Motor Recovery and EEG Power Changes after Robot-Assisted Bilateral Arm Training in Chronic Stroke Patients: A Prospective Pilot Study |
| title_fullStr | Quantification of Upper Limb Motor Recovery and EEG Power Changes after Robot-Assisted Bilateral Arm Training in Chronic Stroke Patients: A Prospective Pilot Study |
| title_full_unstemmed | Quantification of Upper Limb Motor Recovery and EEG Power Changes after Robot-Assisted Bilateral Arm Training in Chronic Stroke Patients: A Prospective Pilot Study |
| title_short | Quantification of Upper Limb Motor Recovery and EEG Power Changes after Robot-Assisted Bilateral Arm Training in Chronic Stroke Patients: A Prospective Pilot Study |
| title_sort | quantification of upper limb motor recovery and eeg power changes after robot assisted bilateral arm training in chronic stroke patients a prospective pilot study |
| url | http://dx.doi.org/10.1155/2018/8105480 |
| work_keys_str_mv | AT marialuisagandolfi quantificationofupperlimbmotorrecoveryandeegpowerchangesafterrobotassistedbilateralarmtraininginchronicstrokepatientsaprospectivepilotstudy AT emanuelaformaggio quantificationofupperlimbmotorrecoveryandeegpowerchangesafterrobotassistedbilateralarmtraininginchronicstrokepatientsaprospectivepilotstudy AT christiangeroin quantificationofupperlimbmotorrecoveryandeegpowerchangesafterrobotassistedbilateralarmtraininginchronicstrokepatientsaprospectivepilotstudy AT silviafrancescastorti quantificationofupperlimbmotorrecoveryandeegpowerchangesafterrobotassistedbilateralarmtraininginchronicstrokepatientsaprospectivepilotstudy AT ilariaboscologalazzo quantificationofupperlimbmotorrecoveryandeegpowerchangesafterrobotassistedbilateralarmtraininginchronicstrokepatientsaprospectivepilotstudy AT martabortolami quantificationofupperlimbmotorrecoveryandeegpowerchangesafterrobotassistedbilateralarmtraininginchronicstrokepatientsaprospectivepilotstudy AT leopoldsaltuari quantificationofupperlimbmotorrecoveryandeegpowerchangesafterrobotassistedbilateralarmtraininginchronicstrokepatientsaprospectivepilotstudy AT alessandropicelli quantificationofupperlimbmotorrecoveryandeegpowerchangesafterrobotassistedbilateralarmtraininginchronicstrokepatientsaprospectivepilotstudy AT andreaswaldner quantificationofupperlimbmotorrecoveryandeegpowerchangesafterrobotassistedbilateralarmtraininginchronicstrokepatientsaprospectivepilotstudy AT paolomanganotti quantificationofupperlimbmotorrecoveryandeegpowerchangesafterrobotassistedbilateralarmtraininginchronicstrokepatientsaprospectivepilotstudy AT nicolasmania quantificationofupperlimbmotorrecoveryandeegpowerchangesafterrobotassistedbilateralarmtraininginchronicstrokepatientsaprospectivepilotstudy |