Translating natural genetic variation to gene expression in a computational model of the Drosophila gap gene regulatory network.
Annotating the genotype-phenotype relationship, and developing a proper quantitative description of the relationship, requires understanding the impact of natural genomic variation on gene expression. We apply a sequence-level model of gap gene expression in the early development of Drosophila to an...
Saved in:
| Main Authors: | Vitaly V Gursky, Konstantin N Kozlov, Ivan V Kulakovskiy, Asif Zubair, Paul Marjoram, David S Lawrie, Sergey V Nuzhdin, Maria G Samsonova |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2017-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0184657 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Canalization of gene expression in the Drosophila blastoderm by gap gene cross regulation.
by: Manu, et al.
Published: (2009-03-01) -
Modeling of gap gene expression in Drosophila Kruppel mutants.
by: Konstantin Kozlov, et al.
Published: (2012-01-01) -
Canalization of gene expression and domain shifts in the Drosophila blastoderm by dynamical attractors.
by: Manu, et al.
Published: (2009-03-01) -
Prediction of gene expression in embryonic structures of Drosophila melanogaster.
by: Anastasia A Samsonova, et al.
Published: (2007-07-01) -
Dissecting the enhancer gene regulatory network in early Drosophila spermatogenesis
by: Patrick van Nierop y Sanchez, et al.
Published: (2025-07-01)