Vulvar Metastasis in Renal Cell Carcinoma: A Case Report Highlighting the Aggressive Nature of Clear Cell Renal Cell Carcinoma
Vulvar cancer is one of the rarest gynecological malignancies. The development of this condition can be associated with either dysplasia linked to human papillomavirus (HPV), primarily affecting younger women, or vulvar dermatoses such as lichen sclerosus, which predominantly affect older women. Ove...
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MDPI AG
2024-12-01
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| Series: | Current Oncology |
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| Online Access: | https://www.mdpi.com/1718-7729/32/1/4 |
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| author | Andreea Boiangiu Ana-Maria Cioca Gabriel-Petre Gorecki Romina-Marina Sima Liana Pleș Marius-Bogdan Novac Ionut-Simion Coman Valentin-Titus Grigorean Vasile Lungu Mihai-Teodor Georgescu George-Alexandru Filipescu |
| author_facet | Andreea Boiangiu Ana-Maria Cioca Gabriel-Petre Gorecki Romina-Marina Sima Liana Pleș Marius-Bogdan Novac Ionut-Simion Coman Valentin-Titus Grigorean Vasile Lungu Mihai-Teodor Georgescu George-Alexandru Filipescu |
| author_sort | Andreea Boiangiu |
| collection | DOAJ |
| description | Vulvar cancer is one of the rarest gynecological malignancies. The development of this condition can be associated with either dysplasia linked to human papillomavirus (HPV), primarily affecting younger women, or vulvar dermatoses such as lichen sclerosus, which predominantly affect older women. Over the last decade, the incidence of vulvar cancer has risen by 0.6% annually, while the relative survival rate has declined. Although metastasis to the vulva is uncommon, it can occur, particularly from cancers in nearby organs such as the cervix, bladder, rectum, or anus. More rarely, metastases from breast cancer and renal cell carcinoma have been reported in the vulva. Vaginal metastases from clear cell renal carcinoma are especially rare. In this article, we present the case of a 56-year-old patient diagnosed with clear cell renal carcinoma, who came to our clinic with a lesion on the right labia, which was identified as a metastasis originating from the kidney. Given the rarity of genital metastases in renal cancer, such cases should be examined and discussed to encourage further research and studies. |
| format | Article |
| id | doaj-art-b0b4c0e7bbcd418485b07535e9671668 |
| institution | Kabale University |
| issn | 1198-0052 1718-7729 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj-art-b0b4c0e7bbcd418485b07535e96716682025-01-24T13:28:19ZengMDPI AGCurrent Oncology1198-00521718-77292024-12-01321410.3390/curroncol32010004Vulvar Metastasis in Renal Cell Carcinoma: A Case Report Highlighting the Aggressive Nature of Clear Cell Renal Cell CarcinomaAndreea Boiangiu0Ana-Maria Cioca1Gabriel-Petre Gorecki2Romina-Marina Sima3Liana Pleș4Marius-Bogdan Novac5Ionut-Simion Coman6Valentin-Titus Grigorean7Vasile Lungu8Mihai-Teodor Georgescu9George-Alexandru Filipescu10Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, RomaniaDepartment of Obstetrics and Gynecology, Elias University Hospital, 011461 Bucharest, RomaniaDepartment of Anesthesia and Intensive Care, Faculty of Medicine, “Titu Maiorescu” University, 031593 Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, 020021 Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, 020021 Bucharest, RomaniaDepartment of Anesthesiology and Intensive Care, University of Medicine and Pharmacy, 200349 Craiova, RomaniaCarol Davila University of Medicine and Pharmacy, 020021 Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, 020021 Bucharest, RomaniaDepartment of General Surgery, CF2 Clinical Hospital, 011464 Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, 020021 Bucharest, RomaniaCarol Davila University of Medicine and Pharmacy, 020021 Bucharest, RomaniaVulvar cancer is one of the rarest gynecological malignancies. The development of this condition can be associated with either dysplasia linked to human papillomavirus (HPV), primarily affecting younger women, or vulvar dermatoses such as lichen sclerosus, which predominantly affect older women. Over the last decade, the incidence of vulvar cancer has risen by 0.6% annually, while the relative survival rate has declined. Although metastasis to the vulva is uncommon, it can occur, particularly from cancers in nearby organs such as the cervix, bladder, rectum, or anus. More rarely, metastases from breast cancer and renal cell carcinoma have been reported in the vulva. Vaginal metastases from clear cell renal carcinoma are especially rare. In this article, we present the case of a 56-year-old patient diagnosed with clear cell renal carcinoma, who came to our clinic with a lesion on the right labia, which was identified as a metastasis originating from the kidney. Given the rarity of genital metastases in renal cancer, such cases should be examined and discussed to encourage further research and studies.https://www.mdpi.com/1718-7729/32/1/4vulvar cancerclear cell renal carcinomametastasisvulvar metastasiskidney tumor |
| spellingShingle | Andreea Boiangiu Ana-Maria Cioca Gabriel-Petre Gorecki Romina-Marina Sima Liana Pleș Marius-Bogdan Novac Ionut-Simion Coman Valentin-Titus Grigorean Vasile Lungu Mihai-Teodor Georgescu George-Alexandru Filipescu Vulvar Metastasis in Renal Cell Carcinoma: A Case Report Highlighting the Aggressive Nature of Clear Cell Renal Cell Carcinoma Current Oncology vulvar cancer clear cell renal carcinoma metastasis vulvar metastasis kidney tumor |
| title | Vulvar Metastasis in Renal Cell Carcinoma: A Case Report Highlighting the Aggressive Nature of Clear Cell Renal Cell Carcinoma |
| title_full | Vulvar Metastasis in Renal Cell Carcinoma: A Case Report Highlighting the Aggressive Nature of Clear Cell Renal Cell Carcinoma |
| title_fullStr | Vulvar Metastasis in Renal Cell Carcinoma: A Case Report Highlighting the Aggressive Nature of Clear Cell Renal Cell Carcinoma |
| title_full_unstemmed | Vulvar Metastasis in Renal Cell Carcinoma: A Case Report Highlighting the Aggressive Nature of Clear Cell Renal Cell Carcinoma |
| title_short | Vulvar Metastasis in Renal Cell Carcinoma: A Case Report Highlighting the Aggressive Nature of Clear Cell Renal Cell Carcinoma |
| title_sort | vulvar metastasis in renal cell carcinoma a case report highlighting the aggressive nature of clear cell renal cell carcinoma |
| topic | vulvar cancer clear cell renal carcinoma metastasis vulvar metastasis kidney tumor |
| url | https://www.mdpi.com/1718-7729/32/1/4 |
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