A scoping review examining the relationship between green tea and skin cancers
Introduction: Skin cancers are among the most commonly diagnosed cancers in the US and are becoming a major public health problem. Polyphenols particularly, (-)-epigallocatechin-3-gallate (EGCG) found in green tea has been shown to have anti-carcinogenic properties in animal models. Chemo-preventati...
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| Format: | Article |
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Edizioni FS
2019-11-01
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| Series: | Journal of Health and Social Sciences |
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| author | Ram Lakhan Louisa Summers Olugbemiga Ekundayo Jedidiah Radosevich Sierra Turner Sangyal Dorjee Vinayak K. Nahar Manoj Sharma |
| author_facet | Ram Lakhan Louisa Summers Olugbemiga Ekundayo Jedidiah Radosevich Sierra Turner Sangyal Dorjee Vinayak K. Nahar Manoj Sharma |
| author_sort | Ram Lakhan |
| collection | DOAJ |
| description | Introduction: Skin cancers are among the most commonly diagnosed cancers in the US and are becoming a major public health problem. Polyphenols particularly, (-)-epigallocatechin-3-gallate (EGCG) found in green tea has been shown to have anti-carcinogenic properties in animal models. Chemo-preventative role of green tea has been studied through epidemiological studies in several cancers such as breast, lung, oral cavity and others. The results have been mixed.
Purpose: The purpose of this study was to conduct a scoping review to examine the relationship between green tea and skin cancers and discuss its implications for humans.
Methods: Literature searches using the keywords “green tea” and skin cancer” were conducted in MEDLINE (PubMed), CINAHL, and Google Scholar. The inclusion criteria were: (1) articles published in the past approximately ten years; (2) in the English language; (3) published in peer-reviewed journals in the above databases; and (4) all accounts of descriptive and epidemiological or evaluation studies. Excluded were articles published before 2008, published in grey literature and non-peer-reviewed journals.
Results: In the literature, systemic and topical applications of green tea polyphenols have shown to have mixed effects against the formation and development of skin cancers in animals. Particularly, EGCG has been found as a contributing factor to inhibit cell invasion, angiogenesis, and metastasis in skin cancer.
Discussion: Use of green tea and its extracts may offer promising implications for use in humans about prevention and retarding the progress of skin cancers but at present, the data are very limited. Large scale randomized controlled trials on the efficacy of green tea and its extracts are required. |
| format | Article |
| id | doaj-art-b0a9d19593b84df7a50aeb44762accfe |
| institution | Kabale University |
| issn | 2499-2240 2499-5886 |
| language | English |
| publishDate | 2019-11-01 |
| publisher | Edizioni FS |
| record_format | Article |
| series | Journal of Health and Social Sciences |
| spelling | doaj-art-b0a9d19593b84df7a50aeb44762accfe2025-01-18T18:20:31ZengEdizioni FSJournal of Health and Social Sciences2499-22402499-58862019-11-014333134410.19204/2019/scpn5A scoping review examining the relationship between green tea and skin cancersRam Lakhan0Louisa Summers1Olugbemiga Ekundayo2Jedidiah Radosevich3Sierra Turner4Sangyal Dorjee5Vinayak K. Nahar6Manoj Sharma7Dr.PH, Assistant Professor, Department of Health and Human Performance, Berea College, Berea, USAPh.D., Professor, Department of Health and Human Performance, Berea College, Berea, USAMD, DrPH, Associate Professor, School of Allied Health, College of Health and Human Services, Northern Kentucky University, Highland Heights, USAStudents, a. BA, Technology and Applied Design (graduated), b. BA, Health Studies (graduated), c. Junior, Biology major (Junior), Berea College, Berea, USAStudents, a. BA, Technology and Applied Design (graduated), b. BA, Health Studies (graduated), c. Junior, Biology major (Junior), Berea College, Berea, USAStudents, a. BA, Technology and Applied Design (graduated), b. BA, Health Studies (graduated), c. Junior, Biology major (Junior), Berea College, Berea, USAMD, PhD, Assistant Professor, Department of Dermatology, School of Medicine, University of Mississippi Medical Center, Jackson, MS, USA and Department of Preventive Medicine, School of Medicine/John D. Bower School of Population Health, University of Mississippi Medical Center, Jackson, MS, USAMBBS, PhD, Professor, Department of Behavioral and Environmental Health, School of Public Health, Jackson State University, USAIntroduction: Skin cancers are among the most commonly diagnosed cancers in the US and are becoming a major public health problem. Polyphenols particularly, (-)-epigallocatechin-3-gallate (EGCG) found in green tea has been shown to have anti-carcinogenic properties in animal models. Chemo-preventative role of green tea has been studied through epidemiological studies in several cancers such as breast, lung, oral cavity and others. The results have been mixed. Purpose: The purpose of this study was to conduct a scoping review to examine the relationship between green tea and skin cancers and discuss its implications for humans. Methods: Literature searches using the keywords “green tea” and skin cancer” were conducted in MEDLINE (PubMed), CINAHL, and Google Scholar. The inclusion criteria were: (1) articles published in the past approximately ten years; (2) in the English language; (3) published in peer-reviewed journals in the above databases; and (4) all accounts of descriptive and epidemiological or evaluation studies. Excluded were articles published before 2008, published in grey literature and non-peer-reviewed journals. Results: In the literature, systemic and topical applications of green tea polyphenols have shown to have mixed effects against the formation and development of skin cancers in animals. Particularly, EGCG has been found as a contributing factor to inhibit cell invasion, angiogenesis, and metastasis in skin cancer. Discussion: Use of green tea and its extracts may offer promising implications for use in humans about prevention and retarding the progress of skin cancers but at present, the data are very limited. Large scale randomized controlled trials on the efficacy of green tea and its extracts are required.green tea; melanoma; non-melanoma skin cancer; review; skin cancer. |
| spellingShingle | Ram Lakhan Louisa Summers Olugbemiga Ekundayo Jedidiah Radosevich Sierra Turner Sangyal Dorjee Vinayak K. Nahar Manoj Sharma A scoping review examining the relationship between green tea and skin cancers Journal of Health and Social Sciences green tea; melanoma; non-melanoma skin cancer; review; skin cancer. |
| title | A scoping review examining the relationship between green tea and skin cancers |
| title_full | A scoping review examining the relationship between green tea and skin cancers |
| title_fullStr | A scoping review examining the relationship between green tea and skin cancers |
| title_full_unstemmed | A scoping review examining the relationship between green tea and skin cancers |
| title_short | A scoping review examining the relationship between green tea and skin cancers |
| title_sort | scoping review examining the relationship between green tea and skin cancers |
| topic | green tea; melanoma; non-melanoma skin cancer; review; skin cancer. |
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