The effects of perfluoroalkyl substance pollution on microbial community and key metabolic pathways in the Pearl River Estuary

The extensive use of perfluoroalkyl substances (PFASs) has raised significant concerns regarding their adverse environmental implications. However, the understanding of their behaviors and biological effects in natural estuarine ecosystems remain limited. This study employed a multidisciplinary appr...

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Main Authors: Wei Lin, Junlin Zhao, Xingqi Wu, Jiakun Jiang, Chunyang Zhou, Jiating Zheng, Cheng Zhang, Ying Guo, Li Wang, How Yong Ng, Song Li, Shengrui Wang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Ecotoxicology and Environmental Safety
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Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325006293
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Summary:The extensive use of perfluoroalkyl substances (PFASs) has raised significant concerns regarding their adverse environmental implications. However, the understanding of their behaviors and biological effects in natural estuarine ecosystems remain limited. This study employed a multidisciplinary approach integrating chemical analysis, biological sequencing, and statistical modeling to comprehensively investigate the distribution of PFASs, as well as their intrinsic relationship with microbial community in the Pearl River Estuary (PRE), a rapidly urbanized area. Our findings demonstrate that the total PFAS concentrations ranged from 52–127 ng L−1 in water, and 2–70 μg kg−1 dry weight in sediment, with notably distinct compositions across habitats. Aquatic microbial communities exhibited higher sensitivity to environmental variables, including PFAS concentrations, attributed to increased stochasticity and reduced spatial turnover. Conversely, sediments harbored microbial communities with higher phylogenetic diversity, rendering them less susceptible to PFAS-induced stress. Furthermore, PFAS concentrations significantly affected microbial carbon, nitrogen, and phosphorus cycling, predominantly through indirect alterations in characteristic genus composition. Importantly, noteworthy variations in impacts were observed between perfluorinated carboxylic acids (PFCAs) and perfluorinated sulfonic acids (PFSAs), which might contingent upon C–F bond dissociation energies. The findings shed light on PFAS ecological roles and interaction patterns with microbial communities in human-impacted estuarine environments.
ISSN:0147-6513