THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPY
The review analyzed the studies and meta-analyses devoted the treatment of multiple drug resistant tuberculosis in combination with antiretroviral therapy as a possible risk factor of adverse events and the worst outcomes of therapy. In total, the analysis included 18 sources from the Russian and En...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
New Terra Publishing House
2019-04-01
|
| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/1252 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849771772227878912 |
|---|---|
| author | S. Yu. Degtyareva E. N. Beloborodova A. V. Pokrovskaya Yu. A. Klimova I. B. Viktorova V. N. Zimina |
| author_facet | S. Yu. Degtyareva E. N. Beloborodova A. V. Pokrovskaya Yu. A. Klimova I. B. Viktorova V. N. Zimina |
| author_sort | S. Yu. Degtyareva |
| collection | DOAJ |
| description | The review analyzed the studies and meta-analyses devoted the treatment of multiple drug resistant tuberculosis in combination with antiretroviral therapy as a possible risk factor of adverse events and the worst outcomes of therapy. In total, the analysis included 18 sources from the Russian and English databases. Most of the studies did not reveal a confident relation between the simultaneous use of antiretroviral and anti-tuberculosis therapy with second line drugs and increased frequency of adverse events. At the same time, in the largest studies, as well as studies devoted to certain adverse events, the authors managed to prove the existence of such a connection. Data on the structure of adverse events also significantly differed in the results obtained by various authors. Most trials were conducted in African countries with a high prevalence of HIV infection. |
| format | Article |
| id | doaj-art-b09edb558ffb4cf596ea8d19b11386aa |
| institution | DOAJ |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2019-04-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-b09edb558ffb4cf596ea8d19b11386aa2025-08-20T03:02:30ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062019-04-01973465310.21292/2075-1230-2019-97-3-46-531252THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPYS. Yu. Degtyareva0E. N. Beloborodova1A. V. Pokrovskaya2Yu. A. Klimova3I. B. Viktorova4V. N. Zimina5People's Friendship University of Russia, MoscowPeople's Friendship University of Russia, MoscowPeople's Friendship University of Russia, Moscow; Central Research Institute of Epidemiology, the Federal Service on Customers' Rights Protection and Human Well-being Surveillance, MoscowPeople's Friendship University of Russia, MoscowNovokuznetsk State Institute for Doctors' Professional Development – Branch of Russian Medical Academy of Continuing Professional Education, NovokuznetskPeople's Friendship University of Russia, MoscowThe review analyzed the studies and meta-analyses devoted the treatment of multiple drug resistant tuberculosis in combination with antiretroviral therapy as a possible risk factor of adverse events and the worst outcomes of therapy. In total, the analysis included 18 sources from the Russian and English databases. Most of the studies did not reveal a confident relation between the simultaneous use of antiretroviral and anti-tuberculosis therapy with second line drugs and increased frequency of adverse events. At the same time, in the largest studies, as well as studies devoted to certain adverse events, the authors managed to prove the existence of such a connection. Data on the structure of adverse events also significantly differed in the results obtained by various authors. Most trials were conducted in African countries with a high prevalence of HIV infection.https://www.tibl-journal.com/jour/article/view/1252antiretroviral therapyanti-tuberculosis therapymdr tb/hiv infectionadverse events |
| spellingShingle | S. Yu. Degtyareva E. N. Beloborodova A. V. Pokrovskaya Yu. A. Klimova I. B. Viktorova V. N. Zimina THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPY Туберкулез и болезни лёгких antiretroviral therapy anti-tuberculosis therapy mdr tb/hiv infection adverse events |
| title | THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPY |
| title_full | THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPY |
| title_fullStr | THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPY |
| title_full_unstemmed | THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPY |
| title_short | THE SAFETY OF TREATMENT OF MULTIPLE DRUG RESISTANT TUBERCULOSIS IN HIV POSITIVE PATIENTS RECEIVING ANTIRETROVIRAL THERAPY |
| title_sort | safety of treatment of multiple drug resistant tuberculosis in hiv positive patients receiving antiretroviral therapy |
| topic | antiretroviral therapy anti-tuberculosis therapy mdr tb/hiv infection adverse events |
| url | https://www.tibl-journal.com/jour/article/view/1252 |
| work_keys_str_mv | AT syudegtyareva thesafetyoftreatmentofmultipledrugresistanttuberculosisinhivpositivepatientsreceivingantiretroviraltherapy AT enbeloborodova thesafetyoftreatmentofmultipledrugresistanttuberculosisinhivpositivepatientsreceivingantiretroviraltherapy AT avpokrovskaya thesafetyoftreatmentofmultipledrugresistanttuberculosisinhivpositivepatientsreceivingantiretroviraltherapy AT yuaklimova thesafetyoftreatmentofmultipledrugresistanttuberculosisinhivpositivepatientsreceivingantiretroviraltherapy AT ibviktorova thesafetyoftreatmentofmultipledrugresistanttuberculosisinhivpositivepatientsreceivingantiretroviraltherapy AT vnzimina thesafetyoftreatmentofmultipledrugresistanttuberculosisinhivpositivepatientsreceivingantiretroviraltherapy AT syudegtyareva safetyoftreatmentofmultipledrugresistanttuberculosisinhivpositivepatientsreceivingantiretroviraltherapy AT enbeloborodova safetyoftreatmentofmultipledrugresistanttuberculosisinhivpositivepatientsreceivingantiretroviraltherapy AT avpokrovskaya safetyoftreatmentofmultipledrugresistanttuberculosisinhivpositivepatientsreceivingantiretroviraltherapy AT yuaklimova safetyoftreatmentofmultipledrugresistanttuberculosisinhivpositivepatientsreceivingantiretroviraltherapy AT ibviktorova safetyoftreatmentofmultipledrugresistanttuberculosisinhivpositivepatientsreceivingantiretroviraltherapy AT vnzimina safetyoftreatmentofmultipledrugresistanttuberculosisinhivpositivepatientsreceivingantiretroviraltherapy |