FAM96B negatively regulates FOSL1 to modulate the osteogenic differentiation and regeneration of periodontal ligament stem cells via ferroptosis

FAM96B negatively regulates FOSL1 to modulate the osteogenic differentiation and regeneration of periodontal ligament stem cells via ferroptosis

Abstract Background Periodontal ligament stem cell (PDLSC)-based therapy is one of the methods to assist bone regeneration. Understanding the functional regulation of PDLSCs and the mechanisms involved is a crucial issue in bone regeneration. This study aimed to explore the roles of the family with...

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Bibliographic Details
Main Authors: Qianyi Qin, Haoqing Yang, Runzhi Guo, Yunfei Zheng, Yiping Huang, Luyuan Jin, Zhipeng Fan, Weiran Li
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Stem Cell Research & Therapy
Subjects:
FAM96B
FOSL1
Periodontal ligament stem cells
Bone regeneration
Osteogenic differentiation
Ferroptosis
Online Access:https://doi.org/10.1186/s13287-024-04083-7
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