Biochemical analysis of human eIF4E-DCP2 interaction: Implications for the relationship between translation initiation and decapping.
All eukaryotic mRNAs bear a 7-methylguanosine cap on their 5' end. The 5' cap enables mRNA translation by binding directly to eIF4E; which further recruits other factors and the 40S ribosome. Additionally, the 5' cap maintains transcript stability; removal of the cap by the enzyme Dcp...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0322271 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|