Role of TIPS in Improving Survival of Patients with Decompensated Liver Disease
Liver cirrhosis is associated with higher morbidity and reduced survival with appearance of portal hypertension and resultant decompensation. Portal decompression plays a key role in improving survival in these patients. Transjugular intrahepatic portosystemic shunts are known to be efficacious in r...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | International Journal of Hepatology |
| Online Access: | http://dx.doi.org/10.4061/2011/398291 |
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| author | Sundeep J. Punamiya Deepak N. Amarapurkar |
| author_facet | Sundeep J. Punamiya Deepak N. Amarapurkar |
| author_sort | Sundeep J. Punamiya |
| collection | DOAJ |
| description | Liver cirrhosis is associated with higher morbidity and reduced survival with appearance of portal hypertension and resultant decompensation. Portal decompression plays a key role in improving survival in these patients. Transjugular intrahepatic portosystemic shunts are known to be efficacious in reducing portal venous pressure and control of complications such as variceal bleeding and ascites. However, they have been associated with significant problems such as poor shunt durability, increased encephalopathy, and unchanged survival when compared with conservative treatment options. The last decade has seen a significant improvement in these complications, with introduction of covered stents, better selection of patients, and clearer understanding of procedural end-points. Use of TIPS early in the period of decompensation also appears promising in further improvement of survival of cirrhotic patients. |
| format | Article |
| id | doaj-art-b080a5b285234e91bfea39593b357f60 |
| institution | Kabale University |
| issn | 2090-3448 2090-3456 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hepatology |
| spelling | doaj-art-b080a5b285234e91bfea39593b357f602025-02-03T01:29:01ZengWileyInternational Journal of Hepatology2090-34482090-34562011-01-01201110.4061/2011/398291398291Role of TIPS in Improving Survival of Patients with Decompensated Liver DiseaseSundeep J. Punamiya0Deepak N. Amarapurkar1Department of Radiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433, SingaporeDepartment of Gastroenterology, Bombay Hospital, 12 Marine Lines, Mumbai 400020, IndiaLiver cirrhosis is associated with higher morbidity and reduced survival with appearance of portal hypertension and resultant decompensation. Portal decompression plays a key role in improving survival in these patients. Transjugular intrahepatic portosystemic shunts are known to be efficacious in reducing portal venous pressure and control of complications such as variceal bleeding and ascites. However, they have been associated with significant problems such as poor shunt durability, increased encephalopathy, and unchanged survival when compared with conservative treatment options. The last decade has seen a significant improvement in these complications, with introduction of covered stents, better selection of patients, and clearer understanding of procedural end-points. Use of TIPS early in the period of decompensation also appears promising in further improvement of survival of cirrhotic patients.http://dx.doi.org/10.4061/2011/398291 |
| spellingShingle | Sundeep J. Punamiya Deepak N. Amarapurkar Role of TIPS in Improving Survival of Patients with Decompensated Liver Disease International Journal of Hepatology |
| title | Role of TIPS in Improving Survival of Patients with Decompensated Liver Disease |
| title_full | Role of TIPS in Improving Survival of Patients with Decompensated Liver Disease |
| title_fullStr | Role of TIPS in Improving Survival of Patients with Decompensated Liver Disease |
| title_full_unstemmed | Role of TIPS in Improving Survival of Patients with Decompensated Liver Disease |
| title_short | Role of TIPS in Improving Survival of Patients with Decompensated Liver Disease |
| title_sort | role of tips in improving survival of patients with decompensated liver disease |
| url | http://dx.doi.org/10.4061/2011/398291 |
| work_keys_str_mv | AT sundeepjpunamiya roleoftipsinimprovingsurvivalofpatientswithdecompensatedliverdisease AT deepaknamarapurkar roleoftipsinimprovingsurvivalofpatientswithdecompensatedliverdisease |