Seizure Associated Takotsubo Syndrome: A Rare Combination

Takotsubo cardiomyopathy (TC) is increasingly recognized in neurocritical care population especially in postmenopausal females. We are presenting a 61-year-old African American female with past medical history of epilepsy, bipolar disorder, and hypertension who presented with multiple episodes of se...

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Main Authors: Htay Htay Kyi, Nour Aljariri Alhesan, Sunil Upadhaya, Samer Al Hadidi
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2017/8458054
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author Htay Htay Kyi
Nour Aljariri Alhesan
Sunil Upadhaya
Samer Al Hadidi
author_facet Htay Htay Kyi
Nour Aljariri Alhesan
Sunil Upadhaya
Samer Al Hadidi
author_sort Htay Htay Kyi
collection DOAJ
description Takotsubo cardiomyopathy (TC) is increasingly recognized in neurocritical care population especially in postmenopausal females. We are presenting a 61-year-old African American female with past medical history of epilepsy, bipolar disorder, and hypertension who presented with multiple episodes of seizures due to noncompliance with antiepileptic medications. She was on telemetry which showed ST alarm. Electrocardiogram (ECG) was ordered and showed ST elevation in anterolateral leads and troponins were positive. Subsequently Takotsubo cardiomyopathy was diagnosed by left ventriculography findings and absence of angiographic evidence of obstructive coronary artery disease. Echocardiogram showed apical hypokinesia, ejection fraction of 40%, and systolic anterior motion of mitral valve with hyperdynamic left ventricle, in the absence of intracoronary thrombus formation in the angiogram. Electroencephalography showed evidence of generalized tonic-clonic seizure. She was treated with supportive therapy. This case illustrates importance of ECG in all patients with seizure irrespective of cardiac symptoms as TC could be the cause of Sudden Unexpected Death in Epilepsy (SUDEP) and may be underdiagnosed and so undertreated.
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publishDate 2017-01-01
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series Case Reports in Cardiology
spelling doaj-art-b07d2d3c295c419fb1c9534008e215782025-02-03T06:07:26ZengWileyCase Reports in Cardiology2090-64042090-64122017-01-01201710.1155/2017/84580548458054Seizure Associated Takotsubo Syndrome: A Rare CombinationHtay Htay Kyi0Nour Aljariri Alhesan1Sunil Upadhaya2Samer Al Hadidi3Hurley Medical Center, Flint, MI, USAHurley Medical Center, Flint, MI, USAHurley Medical Center, Flint, MI, USAHurley Medical Center/Michigan State University, Flint, MI, USATakotsubo cardiomyopathy (TC) is increasingly recognized in neurocritical care population especially in postmenopausal females. We are presenting a 61-year-old African American female with past medical history of epilepsy, bipolar disorder, and hypertension who presented with multiple episodes of seizures due to noncompliance with antiepileptic medications. She was on telemetry which showed ST alarm. Electrocardiogram (ECG) was ordered and showed ST elevation in anterolateral leads and troponins were positive. Subsequently Takotsubo cardiomyopathy was diagnosed by left ventriculography findings and absence of angiographic evidence of obstructive coronary artery disease. Echocardiogram showed apical hypokinesia, ejection fraction of 40%, and systolic anterior motion of mitral valve with hyperdynamic left ventricle, in the absence of intracoronary thrombus formation in the angiogram. Electroencephalography showed evidence of generalized tonic-clonic seizure. She was treated with supportive therapy. This case illustrates importance of ECG in all patients with seizure irrespective of cardiac symptoms as TC could be the cause of Sudden Unexpected Death in Epilepsy (SUDEP) and may be underdiagnosed and so undertreated.http://dx.doi.org/10.1155/2017/8458054
spellingShingle Htay Htay Kyi
Nour Aljariri Alhesan
Sunil Upadhaya
Samer Al Hadidi
Seizure Associated Takotsubo Syndrome: A Rare Combination
Case Reports in Cardiology
title Seizure Associated Takotsubo Syndrome: A Rare Combination
title_full Seizure Associated Takotsubo Syndrome: A Rare Combination
title_fullStr Seizure Associated Takotsubo Syndrome: A Rare Combination
title_full_unstemmed Seizure Associated Takotsubo Syndrome: A Rare Combination
title_short Seizure Associated Takotsubo Syndrome: A Rare Combination
title_sort seizure associated takotsubo syndrome a rare combination
url http://dx.doi.org/10.1155/2017/8458054
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AT nouraljaririalhesan seizureassociatedtakotsubosyndromeararecombination
AT sunilupadhaya seizureassociatedtakotsubosyndromeararecombination
AT sameralhadidi seizureassociatedtakotsubosyndromeararecombination