NSAIDs and Triptans – a (not) New Treatment Option for Migraine
Every day, around 7% of population will experience headache caused by migraine. Migraine is one of the leading causes of years lived with disability, and it also causes significant negative economic impact, as most as the affected population is of working age. Pathogenesis of migraine includes neur...
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| Format: | Article |
| Language: | English |
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Vilnius University Press
2023-12-01
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| Series: | Neurologijos seminarai |
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| Online Access: | https://www.journals.vu.lt/neurologijos_seminarai/article/view/37597 |
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| author | B. Kakta Rasa Mameniškienė |
| author_facet | B. Kakta Rasa Mameniškienė |
| author_sort | B. Kakta |
| collection | DOAJ |
| description |
Every day, around 7% of population will experience headache caused by migraine. Migraine is one of the leading causes of years lived with disability, and it also causes significant negative economic impact, as most as the affected population is of working age. Pathogenesis of migraine includes neurogenic inflammation, which, in turn, causes peripheral sensitization of trigeminal nerve mechanoreceptors. As peripheral sensitization lingers on, central sensitization of the spinal trigeminal nucleus occurs. Non-steroidal anti-inflammatory drugs and triptans are first line treatment of a migraine attack. Nevertheless, when used in combination, these medications deliver a synergistic action. In this article, we review a combination of sumatriptan and naproxen sodium for the treatment of migraine headache as an underused treatment option in Lithuania.
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| format | Article |
| id | doaj-art-b07a23ec0d944a8f8534abf9674919b1 |
| institution | Kabale University |
| issn | 1392-3064 2424-5917 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Vilnius University Press |
| record_format | Article |
| series | Neurologijos seminarai |
| spelling | doaj-art-b07a23ec0d944a8f8534abf9674919b12025-01-20T18:22:00ZengVilnius University PressNeurologijos seminarai1392-30642424-59172023-12-01274(98)10.15388/NS.2023.27.98.7NSAIDs and Triptans – a (not) New Treatment Option for MigraineB. Kakta0Rasa Mameniškienė1Vilnius University, LithuaniaVilnius University, Lithuania Every day, around 7% of population will experience headache caused by migraine. Migraine is one of the leading causes of years lived with disability, and it also causes significant negative economic impact, as most as the affected population is of working age. Pathogenesis of migraine includes neurogenic inflammation, which, in turn, causes peripheral sensitization of trigeminal nerve mechanoreceptors. As peripheral sensitization lingers on, central sensitization of the spinal trigeminal nucleus occurs. Non-steroidal anti-inflammatory drugs and triptans are first line treatment of a migraine attack. Nevertheless, when used in combination, these medications deliver a synergistic action. In this article, we review a combination of sumatriptan and naproxen sodium for the treatment of migraine headache as an underused treatment option in Lithuania. https://www.journals.vu.lt/neurologijos_seminarai/article/view/37597migraineNSAIDstriptanssumatriptan and naproxen sodium |
| spellingShingle | B. Kakta Rasa Mameniškienė NSAIDs and Triptans – a (not) New Treatment Option for Migraine Neurologijos seminarai migraine NSAIDs triptans sumatriptan and naproxen sodium |
| title | NSAIDs and Triptans – a (not) New Treatment Option for Migraine |
| title_full | NSAIDs and Triptans – a (not) New Treatment Option for Migraine |
| title_fullStr | NSAIDs and Triptans – a (not) New Treatment Option for Migraine |
| title_full_unstemmed | NSAIDs and Triptans – a (not) New Treatment Option for Migraine |
| title_short | NSAIDs and Triptans – a (not) New Treatment Option for Migraine |
| title_sort | nsaids and triptans a not new treatment option for migraine |
| topic | migraine NSAIDs triptans sumatriptan and naproxen sodium |
| url | https://www.journals.vu.lt/neurologijos_seminarai/article/view/37597 |
| work_keys_str_mv | AT bkakta nsaidsandtriptansanotnewtreatmentoptionformigraine AT rasamameniskiene nsaidsandtriptansanotnewtreatmentoptionformigraine |