Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs

To know the caudocephalad impact- (CCI-) induced injuries more clearly, 21 adult minipigs, randomly divided into three groups: control group (n=3), group I (n=9), and group II (n=9), were used to perform the CCI experiments on a modified deceleration sled. Configured impact velocity was 0 m/s in the...

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Main Authors: Sishu Guan, Zhikang Liao, Hongyi Xiang, Xiyan Zhu, Zhong Wang, Hui Zhao, Peng Liu, Xinan Lai
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Applied Bionics and Biomechanics
Online Access:http://dx.doi.org/10.1155/2018/2321053
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author Sishu Guan
Zhikang Liao
Hongyi Xiang
Xiyan Zhu
Zhong Wang
Hui Zhao
Peng Liu
Xinan Lai
author_facet Sishu Guan
Zhikang Liao
Hongyi Xiang
Xiyan Zhu
Zhong Wang
Hui Zhao
Peng Liu
Xinan Lai
author_sort Sishu Guan
collection DOAJ
description To know the caudocephalad impact- (CCI-) induced injuries more clearly, 21 adult minipigs, randomly divided into three groups: control group (n=3), group I (n=9), and group II (n=9), were used to perform the CCI experiments on a modified deceleration sled. Configured impact velocity was 0 m/s in the control group, 8 m/s in group I, and 11 m/s in group II. The kinematics and mechanical responses of the subjects were recorded and investigated. The functional change examination and the autopsies were carried out, with which the injuries were evaluated from the Abbreviated Injury Scale (AIS) and the Injury Severity Score (ISS). The subjects in group I and group II experienced the caudocephalad loading at the peak pelvic accelerations of 108.92 ± 58.87 g and 139.13 g ± 78.54 g, with the peak abdomen pressures, 41.24 ± 16.89 kPa and 63.61 ± 65.83 kPa, respectively. The injuries of the spleen, lung, heart, and spine were detected frequently among the tested subjects. The maximal AIS (MAIS) of chest injuries was 4 in group I and 5 in group II, while both the MAIS of abdomen injuries in group I and group II were 5. The ISS in group II was 52.71 ± 6.13, significantly higher than in group I, 26.67 ± 5.02 (p<0.05). The thoracoabdomen CCI injuries and the mechanical response addressed presently may be useful to conduct both the prevention studies against military or civilian injuries.
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spelling doaj-art-b0773a7b2b704ca3b8f000c292bc800c2025-02-03T05:54:24ZengWileyApplied Bionics and Biomechanics1176-23221754-21032018-01-01201810.1155/2018/23210532321053Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using PigsSishu Guan0Zhikang Liao1Hongyi Xiang2Xiyan Zhu3Zhong Wang4Hui Zhao5Peng Liu6Xinan Lai7Department of Spine Surgery, Daping Hospital, Third Military Medical University, Chongqing 400042, ChinaState Key Laboratory of Trauma; Burns & Combined Wound, Institute for Traffic Medicine, Third Military Medical University, Chongqing 400042, ChinaState Key Laboratory of Trauma; Burns & Combined Wound, Institute for Traffic Medicine, Third Military Medical University, Chongqing 400042, ChinaState Key Laboratory of Trauma; Burns & Combined Wound, Institute for Traffic Medicine, Third Military Medical University, Chongqing 400042, ChinaDepartment of Spine Surgery, Daping Hospital, Third Military Medical University, Chongqing 400042, ChinaState Key Laboratory of Trauma; Burns & Combined Wound, Institute for Traffic Medicine, Third Military Medical University, Chongqing 400042, ChinaDepartment of Spine Surgery, Daping Hospital, Third Military Medical University, Chongqing 400042, ChinaState Key Laboratory of Trauma; Burns & Combined Wound, Institute for Traffic Medicine, Third Military Medical University, Chongqing 400042, ChinaTo know the caudocephalad impact- (CCI-) induced injuries more clearly, 21 adult minipigs, randomly divided into three groups: control group (n=3), group I (n=9), and group II (n=9), were used to perform the CCI experiments on a modified deceleration sled. Configured impact velocity was 0 m/s in the control group, 8 m/s in group I, and 11 m/s in group II. The kinematics and mechanical responses of the subjects were recorded and investigated. The functional change examination and the autopsies were carried out, with which the injuries were evaluated from the Abbreviated Injury Scale (AIS) and the Injury Severity Score (ISS). The subjects in group I and group II experienced the caudocephalad loading at the peak pelvic accelerations of 108.92 ± 58.87 g and 139.13 g ± 78.54 g, with the peak abdomen pressures, 41.24 ± 16.89 kPa and 63.61 ± 65.83 kPa, respectively. The injuries of the spleen, lung, heart, and spine were detected frequently among the tested subjects. The maximal AIS (MAIS) of chest injuries was 4 in group I and 5 in group II, while both the MAIS of abdomen injuries in group I and group II were 5. The ISS in group II was 52.71 ± 6.13, significantly higher than in group I, 26.67 ± 5.02 (p<0.05). The thoracoabdomen CCI injuries and the mechanical response addressed presently may be useful to conduct both the prevention studies against military or civilian injuries.http://dx.doi.org/10.1155/2018/2321053
spellingShingle Sishu Guan
Zhikang Liao
Hongyi Xiang
Xiyan Zhu
Zhong Wang
Hui Zhao
Peng Liu
Xinan Lai
Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs
Applied Bionics and Biomechanics
title Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs
title_full Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs
title_fullStr Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs
title_full_unstemmed Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs
title_short Experimental Study of Thoracoabdominal Injuries Suffered from Caudocephalad Impacts Using Pigs
title_sort experimental study of thoracoabdominal injuries suffered from caudocephalad impacts using pigs
url http://dx.doi.org/10.1155/2018/2321053
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