Hematopoietic Stem Cell Transplantation: A Bioethical Lens
Hematopoietic stem cell transplantation (HSCT) is one of a range of therapeutic options available to patients suffering from various diseases. HSCT procedure involves important ethical and legal aspects that can occur at every phase of the procedure: the clinical choice of whether to perform the pro...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2017/1286246 |
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| author | Arcangelo Liso Margherita Neri Francesca Maglietta Raffaele La Russa Emanuela Turillazzi |
| author_facet | Arcangelo Liso Margherita Neri Francesca Maglietta Raffaele La Russa Emanuela Turillazzi |
| author_sort | Arcangelo Liso |
| collection | DOAJ |
| description | Hematopoietic stem cell transplantation (HSCT) is one of a range of therapeutic options available to patients suffering from various diseases. HSCT procedure involves important ethical and legal aspects that can occur at every phase of the procedure: the clinical choice of whether to perform the procedure, pretransplantation preparation regimens, donor selection, stem cell harvest procedure, transplantation phase, and short-term and long-term follow-up care. In this discussion paper, we outline the ethical issue-facing physicians involved in HSCT. Currently, HSCT is a widely accepted treatment for many life-threatening diseases. It thus represents a real therapeutic hope for many patients. It does, however, carry a burden of possible morbidity and mortality. Consequently, there are substantial information and communication issues involved in the consent process for HSCT. In the final decision, the judgements of different parties, such as patients, family members, and healthcare professionals, intersect and overlap and this is particularly true when the patient is a minor. Finally, HSCT is a very expensive procedure. The social and economic concerns of HSCT are discussed within the actual contextual framework of the dramatic increase in healthcare costs and inequalities in healthcare in relation to socioeconomic status, educational status, and ethnicity. |
| format | Article |
| id | doaj-art-b0744c6b10854291a0699a8339f81c42 |
| institution | Kabale University |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-b0744c6b10854291a0699a8339f81c422025-02-03T01:11:42ZengWileyStem Cells International1687-966X1687-96782017-01-01201710.1155/2017/12862461286246Hematopoietic Stem Cell Transplantation: A Bioethical LensArcangelo Liso0Margherita Neri1Francesca Maglietta2Raffaele La Russa3Emanuela Turillazzi4Institute of Hematology, Department of Medical and Surgical Sciences, University of Foggia, Viale Pinto 1, 71122 Foggia, ItalyDepartment of Morphology, Experimental Medicine and Surgery, University of Ferrara, Via Fossato di Mortara 70, 44121 Ferrara, ItalyInstitute of Legal Medicine, Department of Clinical and Experimental Medicine, University of Foggia, Ospedale ‘Colonnello D'Avanzo’, Viale Degli Aviatori 1, 71122 Foggia, ItalyIstituto Clinico-Scientifico Malzoni, 83100 Avellino, ItalyInstitute of Legal Medicine, Department of Clinical and Experimental Medicine, University of Foggia, Ospedale ‘Colonnello D'Avanzo’, Viale Degli Aviatori 1, 71122 Foggia, ItalyHematopoietic stem cell transplantation (HSCT) is one of a range of therapeutic options available to patients suffering from various diseases. HSCT procedure involves important ethical and legal aspects that can occur at every phase of the procedure: the clinical choice of whether to perform the procedure, pretransplantation preparation regimens, donor selection, stem cell harvest procedure, transplantation phase, and short-term and long-term follow-up care. In this discussion paper, we outline the ethical issue-facing physicians involved in HSCT. Currently, HSCT is a widely accepted treatment for many life-threatening diseases. It thus represents a real therapeutic hope for many patients. It does, however, carry a burden of possible morbidity and mortality. Consequently, there are substantial information and communication issues involved in the consent process for HSCT. In the final decision, the judgements of different parties, such as patients, family members, and healthcare professionals, intersect and overlap and this is particularly true when the patient is a minor. Finally, HSCT is a very expensive procedure. The social and economic concerns of HSCT are discussed within the actual contextual framework of the dramatic increase in healthcare costs and inequalities in healthcare in relation to socioeconomic status, educational status, and ethnicity.http://dx.doi.org/10.1155/2017/1286246 |
| spellingShingle | Arcangelo Liso Margherita Neri Francesca Maglietta Raffaele La Russa Emanuela Turillazzi Hematopoietic Stem Cell Transplantation: A Bioethical Lens Stem Cells International |
| title | Hematopoietic Stem Cell Transplantation: A Bioethical Lens |
| title_full | Hematopoietic Stem Cell Transplantation: A Bioethical Lens |
| title_fullStr | Hematopoietic Stem Cell Transplantation: A Bioethical Lens |
| title_full_unstemmed | Hematopoietic Stem Cell Transplantation: A Bioethical Lens |
| title_short | Hematopoietic Stem Cell Transplantation: A Bioethical Lens |
| title_sort | hematopoietic stem cell transplantation a bioethical lens |
| url | http://dx.doi.org/10.1155/2017/1286246 |
| work_keys_str_mv | AT arcangeloliso hematopoieticstemcelltransplantationabioethicallens AT margheritaneri hematopoieticstemcelltransplantationabioethicallens AT francescamaglietta hematopoieticstemcelltransplantationabioethicallens AT raffaelelarussa hematopoieticstemcelltransplantationabioethicallens AT emanuelaturillazzi hematopoieticstemcelltransplantationabioethicallens |