Environmental Factors Promoting Neural Plasticity: Insights from Animal and Human Studies

We do not all grow older in the same way. Some individuals have a cognitive decline earlier and faster than others who are older in years but cerebrally younger. This is particularly easy to verify in people who have maintained regular physical activity and healthy and cognitively stimulating lifest...

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Main Authors: Laura Mandolesi, Francesca Gelfo, Laura Serra, Simone Montuori, Arianna Polverino, Giuseppe Curcio, Giuseppe Sorrentino
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2017/7219461
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author Laura Mandolesi
Francesca Gelfo
Laura Serra
Simone Montuori
Arianna Polverino
Giuseppe Curcio
Giuseppe Sorrentino
author_facet Laura Mandolesi
Francesca Gelfo
Laura Serra
Simone Montuori
Arianna Polverino
Giuseppe Curcio
Giuseppe Sorrentino
author_sort Laura Mandolesi
collection DOAJ
description We do not all grow older in the same way. Some individuals have a cognitive decline earlier and faster than others who are older in years but cerebrally younger. This is particularly easy to verify in people who have maintained regular physical activity and healthy and cognitively stimulating lifestyle and even in the clinical field. There are patients with advanced neurodegeneration, such as Alzheimer’s disease (AD), that, despite this, have mild cognitive impairment. What determines this interindividual difference? Certainly, it cannot be the result of only genetic factors. We are made in a certain manner and what we do acts on our brain. In fact, our genetic basis can be modulated, modified, and changed by our experiences such as education and life events; daily, by sleep schedules and habits; or also by dietary elements. And this can be seen as true even if our experiences are indirectly driven by our genetic basis. In this paper, we will review some current scientific research on how our experiences are able to modulate the structural organization of the brain and how a healthy lifestyle (regular physical activity, correct sleep hygiene, and healthy diet) appears to positively affect cognitive reserve.
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language English
publishDate 2017-01-01
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series Neural Plasticity
spelling doaj-art-b06b2c8435c54283a70d906a12c0c3182025-02-03T06:10:50ZengWileyNeural Plasticity2090-59041687-54432017-01-01201710.1155/2017/72194617219461Environmental Factors Promoting Neural Plasticity: Insights from Animal and Human StudiesLaura Mandolesi0Francesca Gelfo1Laura Serra2Simone Montuori3Arianna Polverino4Giuseppe Curcio5Giuseppe Sorrentino6Department of Movement Sciences and Wellbeing, University “Parthenope”, Via Medina 40, 80133 Naples, ItalyDepartment of Clinical and Behavioural Neurology, IRCCS Fondazione Santa Lucia, Via Ardeatina 306, 00179 Rome, ItalyNeuroimaging Laboratory, IRCCS Fondazione Santa Lucia, Via Ardeatina 306, 00179 Rome, ItalyDepartment of Movement Sciences and Wellbeing, University “Parthenope”, Via Medina 40, 80133 Naples, ItalyDepartment of Movement Sciences and Wellbeing, University “Parthenope”, Via Medina 40, 80133 Naples, ItalyDepartment of Movement Sciences and Wellbeing, University “Parthenope”, Via Medina 40, 80133 Naples, ItalyDepartment of Movement Sciences and Wellbeing, University “Parthenope”, Via Medina 40, 80133 Naples, ItalyWe do not all grow older in the same way. Some individuals have a cognitive decline earlier and faster than others who are older in years but cerebrally younger. This is particularly easy to verify in people who have maintained regular physical activity and healthy and cognitively stimulating lifestyle and even in the clinical field. There are patients with advanced neurodegeneration, such as Alzheimer’s disease (AD), that, despite this, have mild cognitive impairment. What determines this interindividual difference? Certainly, it cannot be the result of only genetic factors. We are made in a certain manner and what we do acts on our brain. In fact, our genetic basis can be modulated, modified, and changed by our experiences such as education and life events; daily, by sleep schedules and habits; or also by dietary elements. And this can be seen as true even if our experiences are indirectly driven by our genetic basis. In this paper, we will review some current scientific research on how our experiences are able to modulate the structural organization of the brain and how a healthy lifestyle (regular physical activity, correct sleep hygiene, and healthy diet) appears to positively affect cognitive reserve.http://dx.doi.org/10.1155/2017/7219461
spellingShingle Laura Mandolesi
Francesca Gelfo
Laura Serra
Simone Montuori
Arianna Polverino
Giuseppe Curcio
Giuseppe Sorrentino
Environmental Factors Promoting Neural Plasticity: Insights from Animal and Human Studies
Neural Plasticity
title Environmental Factors Promoting Neural Plasticity: Insights from Animal and Human Studies
title_full Environmental Factors Promoting Neural Plasticity: Insights from Animal and Human Studies
title_fullStr Environmental Factors Promoting Neural Plasticity: Insights from Animal and Human Studies
title_full_unstemmed Environmental Factors Promoting Neural Plasticity: Insights from Animal and Human Studies
title_short Environmental Factors Promoting Neural Plasticity: Insights from Animal and Human Studies
title_sort environmental factors promoting neural plasticity insights from animal and human studies
url http://dx.doi.org/10.1155/2017/7219461
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