Subacute Disseminated Intravascular Coagulation in a Patient with Liver Metastases of a Renal Cell Carcinoma

Disseminated intravascular coagulation (DIC) is a syndrome characterised by simultaneous bleeding and thromboembolic formation. Its acute form is associated with severe bacterial infections and hematological malignancies. It has a fulminant presentation with prolonged bleeding times and diffuse thro...

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Main Authors: L. C. van der Wekken, R. J. L. F. Loffeld
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2017/1023538
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author L. C. van der Wekken
R. J. L. F. Loffeld
author_facet L. C. van der Wekken
R. J. L. F. Loffeld
author_sort L. C. van der Wekken
collection DOAJ
description Disseminated intravascular coagulation (DIC) is a syndrome characterised by simultaneous bleeding and thromboembolic formation. Its acute form is associated with severe bacterial infections and hematological malignancies. It has a fulminant presentation with prolonged bleeding times and diffuse thrombosis. On the other hand, chronic DIC can be asymptomatic for long periods of time and can be seen in patients with disseminated malignancies. This case report describes a patient who developed DIC within one week and bled profusely from venipuncture wounds. An underlying hepatogenic metastasised renal cell carcinoma appeared to be the cause. This is an uncommon and diagnostically challenging presentation.
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spelling doaj-art-b062bb5ad90b4a9bbd0b71ffc4dcbf792025-02-03T01:10:42ZengWileyCase Reports in Oncological Medicine2090-67062090-67142017-01-01201710.1155/2017/10235381023538Subacute Disseminated Intravascular Coagulation in a Patient with Liver Metastases of a Renal Cell CarcinomaL. C. van der Wekken0R. J. L. F. Loffeld1Department of Internal Medicine, Zaans Medisch Centrum, Zaandam, NetherlandsDepartment of Internal Medicine, Zaans Medisch Centrum, Zaandam, NetherlandsDisseminated intravascular coagulation (DIC) is a syndrome characterised by simultaneous bleeding and thromboembolic formation. Its acute form is associated with severe bacterial infections and hematological malignancies. It has a fulminant presentation with prolonged bleeding times and diffuse thrombosis. On the other hand, chronic DIC can be asymptomatic for long periods of time and can be seen in patients with disseminated malignancies. This case report describes a patient who developed DIC within one week and bled profusely from venipuncture wounds. An underlying hepatogenic metastasised renal cell carcinoma appeared to be the cause. This is an uncommon and diagnostically challenging presentation.http://dx.doi.org/10.1155/2017/1023538
spellingShingle L. C. van der Wekken
R. J. L. F. Loffeld
Subacute Disseminated Intravascular Coagulation in a Patient with Liver Metastases of a Renal Cell Carcinoma
Case Reports in Oncological Medicine
title Subacute Disseminated Intravascular Coagulation in a Patient with Liver Metastases of a Renal Cell Carcinoma
title_full Subacute Disseminated Intravascular Coagulation in a Patient with Liver Metastases of a Renal Cell Carcinoma
title_fullStr Subacute Disseminated Intravascular Coagulation in a Patient with Liver Metastases of a Renal Cell Carcinoma
title_full_unstemmed Subacute Disseminated Intravascular Coagulation in a Patient with Liver Metastases of a Renal Cell Carcinoma
title_short Subacute Disseminated Intravascular Coagulation in a Patient with Liver Metastases of a Renal Cell Carcinoma
title_sort subacute disseminated intravascular coagulation in a patient with liver metastases of a renal cell carcinoma
url http://dx.doi.org/10.1155/2017/1023538
work_keys_str_mv AT lcvanderwekken subacutedisseminatedintravascularcoagulationinapatientwithlivermetastasesofarenalcellcarcinoma
AT rjlfloffeld subacutedisseminatedintravascularcoagulationinapatientwithlivermetastasesofarenalcellcarcinoma